Advancements in Schiff Bases of 1H-Indole-2,3dione: A Versatile Heterocyclic Compound in Pharmacological Field

被引：4
|
作者：
Pradeep, Savitha D. D. [1 ]
Mohanan, Puzhavoorparmbil V. V. [1 ]
机构：
[1] Cochin Univ Sci & Technol, Dept Appl Chem, Kochi 22, Kerala, India
来源：
MINI-REVIEWS IN ORGANIC CHEMISTRY | 2023年 / 20卷 / 01期
关键词：
Isatin; Schiff bases; biological applications; heterocyclic compounds; antidiabetic; antioxidant; GLUCOSIDASE INHIBITORY-ACTIVITY; MEMBRANE-LIPID MONOLAYERS; IN-VITRO; ALPHA-GLUCOSIDASE; MULTIDRUG-RESISTANT; SUBPHASE DISTURBANT; ISATIN DERIVATIVES; ANTIVIRAL ACTIVITY; MOLECULAR DOCKING; ANTITUMOR DRUG;
D O I：
10.2174/1570193X19666220309142035
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Heterocyclic compounds have specific structural peculiarities, imparting immense applications in various fields. This study has explored the medicinal importance of a captive heterocyclic compound, 1H-Indole-2,3dione, commonly known as isatin. The flexibility in the structure of isatin makes it more innovative to have applications in the biological and analytical fields. In this mini-review, we have discussed Schiff bases of isatin having activities, such as antidiabetic, antioxidant, antidiabetic, antimalarial, antiviral, anticonvulsant, anti-inflammatory and analgesic activity, and also the importance of this compound in various fields based on the reports mainly focussed on the current and past couple of years.
引用
收藏
页码：45 / 54
页数：10
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