Plm-102, a Next Generation FLT3 Inhibitor, Shows Potent Anti-Leukemic Activity on Resistance to Gilteritinib in FLT3 Mutated Acute Myeloid Leukemia

被引：0
|
作者：
Lee, Jae-Seon [1 ]
Park, Min Ji [1 ]
Sun, Ningning [1 ]
Park, Jin-Hee [1 ]
Oh, Su-jin [1 ]
Moon, Miran [1 ]
Kim, Myung Jin [1 ]
Jang, Soo Yeon [1 ]
Kim, Yong-Chul [1 ]
机构：
[1] PeLeMed, Seoul, South Korea
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-180483
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [41] FLT3 inhibitors in acute myeloid leukemia
    el-Shami, Khaled
    Stone, Richard M.
    Smith, B. Douglas
    EXPERT REVIEW OF HEMATOLOGY, 2008, 1 (02) : 153 - 160
  • [42] FLT3 Inhibitors for Acute Myeloid Leukemia
    Lancet, Jeffrey E.
    CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY, 2015, 13 (09) : 573 - 575
  • [43] FLT3 inhibitors in acute myeloid leukemia
    Pastore, Domenico
    DRUGS AND CELL THERAPIES IN HEMATOLOGY, 2016, 4 (01): : 14 - 21
  • [44] Gilteritinib is a clinically active FLT3 inhibitor with broad activity against FLT3 kinase domain mutations
    Tarver, Theodore C.
    Hill, Jason E.
    Rahmat, Leena
    Perl, Alexander E.
    Bahceci, Erkut
    Mori, Kenichi
    Smith, Catherine C.
    BLOOD ADVANCES, 2020, 4 (03) : 514 - 524
  • [45] Venetoclax in Combination with Gilteritinib Demonstrates Molecular Clearance of FLT3 mutation in Relapsed/Refractory FLT3Mutated Acute Myeloid Leukemia
    Daver, Naval
    Perl, Alexander E.
    Maly, Joseph
    Levis, Mark
    Ritchie, Ellen
    Litzow, Mark R.
    McCloskey, James
    Smith, Catherine C.
    Schiller, Gary J.
    Bradley, Terrence
    Tiu, Ramon V.
    Naqvi, Kiran
    Dail, Monique
    Siddani, Satya
    Wang, Jing
    Chyla, Brenda
    Lee, Paul
    Altman, Jessica K.
    BLOOD, 2021, 138
  • [46] OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia
    Bartholomew J. Eisfelder
    Caner Saygin
    Joseph Wynne
    Margaret W. Colton
    Mariafausta Fischietti
    Elspeth M. Beauchamp
    Jason X. Cheng
    Olatoyosi Odenike
    Gail Roboz
    Houda Alachkar
    Wendy Stock
    Blood Cancer Journal, 11
  • [47] OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia
    Eisfelder, Bartholomew J.
    Saygin, Caner
    Wynne, Joseph
    Colton, Margaret W.
    Fischietti, Mariafausta
    Beauchamp, Elspeth M.
    Cheng, Jason X.
    Odenike, Olatoyosi
    Roboz, Gail
    Alachkar, Houda
    Stock, Wendy
    BLOOD CANCER JOURNAL, 2021, 11 (03)
  • [48] Incorporating FLT3 inhibitors in the frontline treatment of FLT3 mutant acute myeloid leukemia
    Wang, Eunice S.
    BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2019, 32 (02) : 154 - 162
  • [49] THE FLT3 INHIBITOR GILTERITINIB HAS ACTIVITY IN PATIENTS WITH AML
    不详
    CANCER DISCOVERY, 2017, 7 (08) : 794 - 794
  • [50] Gilteritinib-Based Combination Therapy in Adult Relapsed/Refractory FLT3 Mutated Acute Myeloid Leukemia
    Chen, Nianci
    Pan, Jiajia
    Zhou, Yile
    Mao, Liping
    Lou, Yinjun
    Qian, Jiejing
    Xu, Gaixiang
    Wei, Juying
    Zhou, De
    Shou, Lihong
    Li, Huang
    Yan, Minchao
    Zeng, Hui
    Fan, Cuihua
    Wu, Gongqiang
    Feng, Weiying
    Tong, Hongyan
    Jin, Jie
    Wang, Huafeng
    BLOOD, 2023, 142
12345