Topical Ruxolitinib for Chronic Cutaneous GvHD: Promising Results of a Phase 2 Clinical Trial

被引:0
|
作者
Markova, Alina [1 ]
Papadopoulos, Esperanza B. [2 ]
Dusza, Stephen [1 ]
Ostojic, Jelena [3 ]
Ai, Rizi [3 ]
Maier, Tara [1 ]
Lacouture, Mario [1 ]
Tamari, Roni
Gyurkocza, Boglarka
Shaffer, Brian C. [2 ]
Scordo, Michael [2 ]
Perales, Miguel-Angel [2 ]
Harris, Andrew [4 ]
Ponce, Doris M. [2 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Med, Dermatol Serv, New York, NY USA
[2] Mem Sloan Kettering Canc Ctr, Dept Med, Adult Bone Marrow Transplantat Serv, New York, NY USA
[3] DermTech, San Diego, CA USA
[4] Mem Sloan Kettering Canc Ctr, Dept Pediat, Pediat Stem Cell Transplantat & Cellular Therapie, New York, NY USA
关键词
D O I
10.1182/blood-2023-182198
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:4
相关论文
共 50 条
  • [41] A Clinical Trial Design for Evaluating Topical Antimicrobials in Chronic Wounds: The BLEU Trial
    Serena, Thomas
    King, Emily
    Boyer, Theresa
    Harrell, Khristina
    LIFE-BASEL, 2023, 13 (10):
  • [42] Ruxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial
    Rosmarin, David
    Pandya, Amit G.
    Lebwohl, Mark
    Grimes, Pearl
    Hamzavi, Iltefat
    Gottlieb, Alice B.
    Butler, Kathleen
    Kuo, Fiona
    Sun, Kang
    Ji, Tao
    Howell, Michael D.
    Harris, John E.
    LANCET, 2020, 396 (10244): : 110 - 120
  • [43] A multi-institution phase I trial of ruxolitinib in chronic myelomonocytic leukemia (CMML)
    Padron, Eric
    Dezern, Amy Elizabeth
    Vaddi, Kris
    Scherle, Peggy A.
    Zhang, Qing
    Ma, Yan
    Balasis, Maria
    Tinsley, Sara
    Ramadan, Hanadi
    Zimmerman, Casandra
    Steensma, David P.
    Roboz, Gail J.
    Lancet, Jeffrey E.
    List, Alan F.
    Sekeres, Mikkael A.
    Komrokji, Rami S.
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [44] Topical terbinafine in the treatment of cutaneous leishmaniasis: triple blind randomized clinical trial
    Farajzadeh S.
    Heshmatkhah A.
    Vares B.
    Mohebbi E.
    Mohebbi A.
    Aflatoonian M.
    Eybpoosh S.
    Sharifi I.
    Aflatoonian M.R.
    Shamsi Meymandi S.
    Fekri A.R.
    Mostafavi M.
    Journal of Parasitic Diseases, 2016, 40 (4) : 1159 - 1164
  • [45] ACUTE GVHD IN PATIENTS ENROLLED IN THE PROSPECTIVE, INTERNATIONAL FORUM TRIAL: CLINICAL RESULTS
    Merli, Pietro
    Algeri, Mattia
    Poetschger, Ulrike
    Bader, Peter
    Ifversen, Marianne
    Stein, Jerry
    Sedlacek, Petr
    Buechner, Jochen
    Ansari, Marc
    Kalwak, Krzysztof
    Dalle, Jean-Hugues
    Peters, Christina
    Locatelli, Franco
    Lawitschka, Anita
    BONE MARROW TRANSPLANTATION, 2024, 59 : 122 - 123
  • [46] Serlopitant for the treatment of chronic pruritus: Results of a randomized, multicenter, placebo-controlled phase 2 clinical trial
    Yosipovitch, Gil
    Stander, Sonja
    Kerby, Matthew B.
    Larrick, James W.
    Perlman, Andrew J.
    Schnipper, Edward F.
    Zhang, Xiaoming
    Tang, Jean Y.
    Luger, Thomas
    Steinhoff, Martin
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2018, 78 (05) : 882 - +
  • [47] A Multicenter, Retrospective Study Evaluating Clinical Outcomes of Ruxolitinib Therapy In Heavily Pretreated Chronic GVHD Patients With Steroid Failure
    White, Jennifer
    Elemary, Mohamed
    Linn, Swe Mar
    Novitzky-Basso, Igor
    Culos, Samantha
    Tan, Sui Keat
    Kelly, Kate
    Deotare, Uday
    Xenocostas, Anargyros
    Hamad, Nada
    Law, Arjun
    Kumar, Rajat
    Kim, Dennis Dong Hwan
    TRANSPLANTATION AND CELLULAR THERAPY, 2023, 29 (02): : 120.e1 - 120.e9
  • [48] Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial
    Cutler, Corey
    Kim, Haesook T.
    Bindra, Bhavjot
    Sarantopoulos, Stefanie
    Ho, Vincent T.
    Chen, Yi-Bin
    Rosenblatt, Jacalyn
    McDonough, Sean
    Watanaboonyongcharoen, Phandee
    Armand, Philippe
    Koreth, John
    Glotzbecker, Brett
    Alyea, Edwin
    Blazar, Bruce R.
    Soiffer, Robert J.
    Ritz, Jerome
    Antin, Joseph H.
    BLOOD, 2013, 122 (08) : 1510 - 1517
  • [49] Topical Isopropyl Unoprostone for Retinitis Pigmentosa: Microperimetric Results of the Phase 2 Clinical Study
    Yamamoto, Shuichi
    Sugawara, Takeshi
    Murakami, Akira
    Nakazawa, Mitsuru
    Nao-i, Nobuhisa
    Machida, Shigeki
    Wada, Yuko
    Mashima, Yukihiko
    Myake, Yozo
    OPHTHALMOLOGY AND THERAPY, 2012, 1 (01)
  • [50] Topical Isopropyl Unoprostone for Retinitis Pigmentosa: Microperimetric Results of the Phase 2 Clinical Study
    Shuichi Yamamoto
    Takeshi Sugawara
    Akira Murakami
    Mitsuru Nakazawa
    Nobuhisa Nao-i
    Shigeki Machida
    Yuko Wada
    Yukihiko Mashima
    Yozo Myake
    Ophthalmology and Therapy, 2012, 1 (1)