Progressive multifocal leukoencephalopathy (PML) treated with pembrolizumab in a patient with mosaic STAT3 gain-of-function mutation

被引：0
|
作者：
Sheng, Gloria [1 ]
Butte, Manish [2 ,3 ]
Garcia-Lloret, Maria [1 ]
Anderson, Lorraine [1 ]
机构：
[1] Univ Calif Los Angeles, Los Angeles, CA 90024 USA
[2] Univ Calif Los Angeles, Dept Pediat, Los Angeles, CA USA
[3] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA USA
来源：
CLINICAL IMMUNOLOGY | 2023年 / 250卷
关键词：
STAT3; Human polyomavirus 2; JC virus; Progressive multifocal leukoencephalopathy;
D O I：
10.1016/j.clim.2023.109453
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
106
引用
收藏
页码：56 / 56
页数：1
相关论文
共 50 条
  • [41] STAT 1 GAIN-OF-FUNCTION MUTATION IN PATIENT WITH VISCERAL LEISHMANIASIS AND SECONDARY HEMOPHAGOCYTIC LYMPHOHYSTIOCITOSIS
    Lyra Marques, Paula Teixeira
    Augusto Moura Falcao, Ana Carla
    Oliveira Filho, Joao Bosco
    JOURNAL OF CLINICAL IMMUNOLOGY, 2017, 37 (02) : 263 - 264
  • [42] Identification of a gain-of-function STAT3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome
    Walker, S.
    Wang, C.
    Walradt, T.
    Hong, B. S.
    Tanner, J. R.
    Levinsohn, J.
    Goh, G.
    Subtil, A.
    Lessin, S. R.
    Heymann, W.
    Vonderheid, E. C.
    King, B. A.
    Lifton, R.
    Choi, J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2016, 136 (05) : S5 - S5
  • [43] Identification of a gain-of-function STAT3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome
    Walker, Sarah
    Wang, Chen
    Walradt, Trent
    Hong, Bok Sil
    Tanner, Justin R.
    Levinsohn, Jonathan L.
    Goh, Gerald
    Subtil, Antonio
    Lessin, Stuart R.
    Heymann, Warren R.
    Vonderheid, Eric C.
    King, Brett A.
    Lifton, Richard P.
    Choi, Jaehyuk
    BLOOD, 2016, 127 (07) : 948 - 951
  • [44] A case of enteropathy secondary to STAT1 gain-of-function mutation successfully treated with tofacitinib
    Lees, Robert
    Wyatt, Nicola
    Boag, Stephen
    Burns, Siobhan
    Lamb, Chris
    Speight, Ally
    GUT, 2023, 72 (SUPPL_2) : A100 - A100
  • [45] Treatment of Interstitial Lung Disease in STAT3 Gain-of-Function Using JAK Inhibitors
    Carmona, M. D. Silva
    Vogel, T.
    Marchal, S.
    Guesmi, M.
    Dubus, J.
    Baravalle, M.
    Leroy, S.
    Marquette, C.
    Fabre, A.
    Barlogis, V.
    Leiding, J.
    Forbes, L.
    Giovannini-Chami, L.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
  • [46] Janus kinase inhibitors ameliorate clinical symptoms in patients with STAT3 gain-of-function
    Kaneko, Shuya
    Sakura, Fumiaki
    Tanita, Kay
    Shimbo, Asami
    Nambu, Ryusuke
    Yoshida, Masashi
    Umetsu, Shuichiro
    Inui, Ayano
    Okada, Chizuru
    Tsumura, Miyuki
    Yamada, Mamiko
    Suzuki, Hisato
    Kosaki, Kenjiro
    Ohara, Osamu
    Shimizu, Masaki
    Morio, Tomohiro
    Okada, Satoshi
    Kanegane, Hirokazu
    IMMUNOTHERAPY ADVANCES, 2023, 3 (01):
  • [47] Progressive Multifocal Leukoencephalopathy Associated with Idiopathic CD4+Lymphocytopenia in a Patient with Heterozygous STAT4 Mutation
    Acarli, Ayse Nur Ozdag
    Tuzer, Can
    Gunduz, Tuncay
    Ismayilov, Rashad
    Pariltay, Erhan
    Alpman, Asude
    Aykut, Ayca
    Demir, Semra
    Soylemezoglu, Figen
    Kurtuncu, Murat
    Eraksoy, Mefkure
    NEUROLOGY, 2020, 94 (15)
  • [48] STAT1 Gain-of-Function Mutation in Patient with Visceral Leishmaniasis and Secondary Hemophagocytic Lymphohystiocitosis
    de Oliveira Filho, Joao Bosco
    Moura, Ana Carla
    Lyra, Paula Teixeira
    Souza, Edvaldo da Silva
    JOURNAL OF CLINICAL IMMUNOLOGY, 2017, 37 : S34 - S34
  • [49] GAIN-OF-FUNCTION STAT1 MUTATIONS ALTER STAT3 ACTIVATION IN PATIENTS WITH CHRONIC MUCOCUTANEOUS CANDIDIASIS
    Zheng, J.
    Rowan, A. D.
    Gennery, A. R.
    Abinun, M.
    Lilic, D.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2012, 32 : 203 - 203
  • [50] Successful Treatment of Interstitial Lung Disease in STAT3 Gain-of-Function Using JAK Inhibitors
    Silva-Carmona, Manuel
    Vogel, Tiphanie P.
    Marchal, Sarah
    Guesmi, Myriam
    Dubus, Jean-Christophe
    Leroy, Sylvie
    Fabre, Alexandre
    Barlogis, Vincent
    Forbes, Lisa R.
    Giovannini-Chami, Lisa
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 202 (06) : 893 - 897
12345