New insights into balancing wound healing and scarless skin repair

被引：23
|
作者：
Zhou, Shengxi [1 ]
Xie, Mengbo [1 ]
Su, Jingjing [1 ]
Cai, Bingjie [2 ]
Li, Jingan [3 ,4 ]
Zhang, Kun [1 ,5 ]
机构：
[1] Zhengzhou Univ, Sch Life Sci, Zhengzhou, Henan, Peoples R China
[2] Zhengzhou Univ, Affiliated Hosp 1, Dept Dermatol, Zhengzhou, Henan, Peoples R China
[3] Zhengzhou Univ, Sch Mat Sci & Engn, Zhengzhou, Henan, Peoples R China
[4] Zhengzhou Univ, Sch Mat Sci & Engn, 100, Sci Rd, Zhengzhou 450001, Henan, Peoples R China
[5] Zhengzhou Univ, Sch Life Sci, Zhengzhou 450001, Henan, Peoples R China
来源：
JOURNAL OF TISSUE ENGINEERING | 2023年 / 14卷
基金：
中国国家自然科学基金;
关键词：
Wound healing; skin regeneration; scar; fibroblasts; extracellular matrix; HYALURONIC-ACID; GROWTH-FACTOR; CHITOSAN HYDROGEL; CELLS; MATRIX; ANTIBACTERIAL; TISSUE; GENE; RECONSTRUCTION; NANOPARTICLES;
D O I：
10.1177/20417314231185848
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Scars caused by skin injuries after burns, wounds, abrasions and operations have serious physical and psychological effects on patients. In recent years, the research of scar free wound repair has been greatly expanded. However, understanding the complex mechanisms of wound healing, in which various cells, cytokines and mechanical force interact, is critical to developing a treatment that can achieve scarless wound healing. Therefore, this paper reviews the types of wounds, the mechanism of scar formation in the healing process, and the current research progress on the dual consideration of wound healing and scar prevention, and some strategies for the treatment of scar free wound repair.
引用
收藏
页数：28
相关论文
共 50 条
  • [41] An in vivo mouse excisional wound model of scarless healing
    Colwell, Amy S.
    Krummel, Thomas M.
    Longaker, Michael T.
    Lorenz, H. Peter
    [J]. PLASTIC AND RECONSTRUCTIVE SURGERY, 2006, 117 (07) : 2292 - 2296
  • [42] Differential expression analysis of scarless wound healing by microarray
    Kathju, Sandeep
    Oswald, Duane
    Satish, Latha
    Johnson, Sandra
    Erdos, Geza
    Singh, Mandal
    Post, Christopher J.
    Ehrlich, Garth D.
    [J]. WOUND REPAIR AND REGENERATION, 2007, 15 (02) : A20 - A20
  • [43] FETAL WOUND-HEALING - A BIOCHEMICAL-STUDY OF SCARLESS HEALING
    SIEBERT, JW
    BURD, DAR
    MCCARTHY, JG
    WEINZWEIG, J
    EHRLICH, HP
    [J]. PLASTIC AND RECONSTRUCTIVE SURGERY, 1990, 85 (04) : 495 - 502
  • [44] WHAT WE CAN DO FOR SCARLESS WOUND HEALING
    Aramaki-Hattori, N.
    Nagashima, H.
    Sakai, S.
    Okabe, K.
    Kishi, K.
    [J]. WOUND REPAIR AND REGENERATION, 2019, 27 (05) : A1 - A1
  • [45] Scarless wound healing: finding the right cells and signals
    Tripp Leavitt
    Michael S. Hu
    Clement D. Marshall
    Leandra A. Barnes
    H. Peter Lorenz
    Michael T. Longaker
    [J]. Cell and Tissue Research, 2016, 365 : 483 - 493
  • [46] PGLCNAC NANOFIBERS STIMULATE A SCARLESS WOUND HEALING PROGRAM
    Lindner, H. B.
    Demcheva, M.
    Seth, A.
    Bradshaw, A.
    Vournakis, J.
    Muise-Helmericks, R. C.
    [J]. WOUND REPAIR AND REGENERATION, 2012, 20 (02) : A29 - A29
  • [47] Scarless wound healing: finding the right cells and signals
    Leavitt, Tripp
    Hu, Michael S.
    Marshall, Clement D.
    Barnes, Leandra A.
    Lorenz, H. Peter
    Longaker, Michael T.
    [J]. CELL AND TISSUE RESEARCH, 2016, 365 (03) : 483 - 493
  • [48] Integrins regulation of wound healing processes: insights for chronic skin wound therapeutics
    Yu, Dong
    Lu, Zhaoyu
    Nie, Fengsong
    Chong, Yang
    [J]. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2024, 14
  • [49] SCARLESS WOUND-HEALING - IMPLICATIONS FOR THE AESTHETIC SURGEON
    CHANG, J
    SIEBERT, JW
    SCHENDEL, SA
    PRESS, BHJ
    LONGAKER, MT
    [J]. AESTHETIC PLASTIC SURGERY, 1995, 19 (03) : 237 - 241
  • [50] Optimal Support of Wound Healing: New Insights
    Baron, Jens Malte
    Glatz, Martin
    Proksch, Ehrhardt
    [J]. DERMATOLOGY, 2020, 236 (06) : 593 - 600
12345