Optimization of Packaging Efficiency for Adeno-Associated Virus by Evaluating Production Process Parameters Using Ambr 250® High-Throughput Platform

被引:0
|
作者
Chen, Tsai-Yu [1 ]
Wang, Peng [2 ]
McAllister, James [3 ]
Duong, Tam [2 ]
Gao, Xiang [2 ]
Gu, Bingnan [2 ]
Dong, Wenling [1 ]
机构
[1] Lonza Houston Inc, Proc Dev, Houston, TX USA
[2] Lonza Houston Inc, Res & Dev, Houston, TX USA
[3] Lonza, Appl Stat, Portsmouth, NH USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
1465
引用
收藏
页码:691 / 691
页数:1
相关论文
共 49 条
  • [31] Process Development for the Production and Purification of Adeno-Associated Virus (AAV)2 Vector using Baculovirus-Insect Cell Culture System
    Nasimuzzaman, Md
    Villaveces, Sophia
    van der Loo, Johannes C. M.
    Alla, Sivani
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2022, (179):
  • [32] Preserving High Transduction Efficiency - Serotype Agnostic Purification of Adeno-Associated Virus Using Adsorbents Functionalized with In Silco Discovered Peptide Ligand
    Shastry, Shriarjun
    Menegatti, Stefano
    Chu, Wenning
    MOLECULAR THERAPY, 2023, 31 (04) : 12 - 13
  • [33] Development and production of recombinant Adeno Associated Virus (rAAV) at 1 to 1,000L scale using a Platform process
    Agbogbo, F.
    Wesel, S.
    Krishnamoorthy, G.
    Craddick, A.
    Davis, A.
    Dismuke, D.
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A42 - A42
  • [34] High-Throughput Multiplex Screening of Bacteria, Fungi, Virus, and Protozoa Associated with Vaginosis/Vaginitis Research Using the OpenArray Platform
    Patel, S.
    Li, K.
    Probert, W.
    Huang, B.
    Fantin, N.
    Pagani, I.
    Zeringer, E.
    Brzoska, P.
    Pun, N.
    Diamond, E.
    Trotta, J.
    Varma, K.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2015, 17 (06): : 856 - 856
  • [35] CAP-GT Platform: A Scalable AAV Production System Using Helper Virus-Free Adeno-Associated Viral Vector Packaging/Producer Cell Lines Based in Human Suspension Cells
    Goncalves, Ines do Carmo
    Hein, Kerstin
    Hudjetz, Ben
    Strempel, Nikola
    Riebesehl, Nina
    Kewes, Helmut
    Bauer, Thu
    Bialek, Corinna
    Wissing, Silke
    Faust, Nicole
    MOLECULAR THERAPY, 2019, 27 (04) : 224 - 225
  • [37] Large-Scale Production of High-Quality Recombinant Adeno-Associated Virus Using Short-Term Zonal Ultracentrifugation
    Wada, Mikako
    Uchida, Naoya
    Posadas-Herrera, Guillermo
    Hayashita-Kinoh, Hiromi
    Tsunekawa, Yuji
    Hirai, Yukihiko
    Okada, Takashi
    MOLECULAR THERAPY, 2023, 31 (04) : 605 - 605
  • [38] Separate control of rep and cap expression using mutant and wild-type LoxP sequences and improved packaging system for adeno-associated virus vector production
    Hiroaki Mizukami
    Takashi Okada
    Yoji Ogasawara
    Takashi Matsushita
    Masashi Urabe
    Akihiro Kume
    Keiya Ozawa
    Molecular Biotechnology, 2004, 27 : 7 - 14
  • [39] Separate control of Rep and Cap expression using mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production
    Mizukami, H
    Okada, T
    Ogasawara, Y
    Matsushita, T
    Urabe, M
    Kume, A
    Ozawa, K
    MOLECULAR BIOTECHNOLOGY, 2004, 27 (01) : 7 - 14
  • [40] Overexpression of Indoleamine Dioxygenase in Rat Liver Allografts Using a High-Efficiency Adeno-Associated Virus Vector Does Not Prevent Acute Rejection
    Laurence, Jerome M.
    Wang, Chuanmin
    Zheng, Maolin
    Cunningham, Sharon
    Earl, John
    Tay, Szun Szun
    Allen, Richard D. M.
    McCaughan, Geoffrey W.
    Alexander, Ian E.
    Bishop, G. Alex
    Sharland, Alexandra F.
    LIVER TRANSPLANTATION, 2009, 15 (02) : 233 - 241