Adipose mesenchymal stem cells from COPD patients are capable of restoring elastase-induced emphysema in a murine experimental model

被引：0
|
作者：
Martin Medina, Aina [1 ]
Rio, Carlos [1 ]
Jahn, Andreas K. [1 ]
Calvo Bota, Alba Martina [1 ]
De Francisco Casado, Ma Teresa [2 ]
Pont Antona, Pere Joan [2 ]
Gigirey Castro, Orlando [3 ]
Francisco Carvajal, Angel [3 ]
Villena Portella, Cristina [4 ,5 ]
Gomez Bellvert, Cristina [6 ]
Iglesias, Amanda [4 ,7 ]
Calvo Benito, Javier [8 ]
Gaya Puig, Antoni [8 ]
Ortiz, Luis A. [9 ]
Sala-Llinas, Ernest [4 ,10 ]
机构：
[1] IdISBa, Inflamac ImmflamatInflammat Repair & Canc Resp Di, Palma De Mallorca, Spain
[2] Univ Ies Illes Balears UIB, Palma De Mallorca, Spain
[3] Hosp Univ Son Espases, Dept Thorac Surg, Palma De Mallorca, Spain
[4] IdISBa, iRespire, Palma De Mallorca, Spain
[5] Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Resp CIBERES, CIBERES Pulm Biobank Consortium, Palma De Mallorca, Spain
[6] Hosp Univ Son Espases, Dept Pathol, Palma De Mallorca, Spain
[7] Inst Salud Carlos III CIBERINFEC, Ctr Invest Biomed Red Enfermedades Infecciosas, Madrid, Spain
[8] IdISBa, Banc Teixits Blood & Tissue Bank Balear Islands F, Cell Therapy & Tissue Engn Grp TERCIT, Palma De Mallorca, Spain
[9] Univ Pittsburgh, Dept Environm & Occupat Hlth, Pittsburgh, PA USA
[10] Hosp Univ Son Espases, Dept Pulm Med, Palma De Mallorca, Spain
来源：
EUROPEAN RESPIRATORY JOURNAL | 2023年 / 62卷
关键词：
D O I：
10.1183/13993003.congress-2023.PA5241
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [11] The Therapeutic Effects of Optimal Dose of Mesenchymal Stem Cells in a Murine Model of an Elastase Induced-Emphysema
    Kim, You-Sun
    Kim, Ji-Young
    Huh, Jin Won
    Lee, Sei Won
    Choi, Soo Jin
    Oh, Yeon-Mok
    TUBERCULOSIS AND RESPIRATORY DISEASES, 2015, 78 (03) : 239 - 245
  • [12] Mesenchymal stromal cells-based therapy in a murine model of elastase-induced emphysema: Simvastatin as a potential adjuvant in cellular homing
    de Faria, Carolina Arruda
    Silva Junior, Wilson Araujo
    Coelho, Karoline Brito Caetano Andrade
    Bassi, Mirian
    Colombari, Eduardo
    Zanette, Dalila Luciola
    Ribeiro-Paes, Joao Tadeu
    PULMONARY PHARMACOLOGY & THERAPEUTICS, 2021, 70
  • [13] Elastase-induced pulmonary emphysema: insights from experimental models
    Antunes, Mariana A.
    Rocco, Patricia R. M.
    ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS, 2011, 83 (04): : 1385 - 1395
  • [14] Understanding the modulations of glycero-lysophospholipids in an elastase-induced murine emphysema model
    Isago, Hideaki
    Uranbileg, Baasanjav
    Mitani, Akihisa
    Kurano, Makoto
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 694
  • [15] Cell therapy with adipose tissue-derived stem/stromal cells for elastase-induced pulmonary emphysema in rats
    Furuya, Naoki
    Takenaga, Mitsuko
    Miyazawa, Teruomi
    EUROPEAN RESPIRATORY JOURNAL, 2012, 40
  • [16] Cell therapy with adipose tissue-derived stem/stromal cells for elastase-induced pulmonary emphysema in rats
    Furuya, Naoki
    Takenaga, Mitsuko
    Ohta, Yuki
    Tokura, Yukie
    Hamaguchi, Akemi
    Sakamaki, Aya
    Kida, Hirotaka
    Handa, Hiroshi
    Nishine, Hiroki
    Mineshita, Masamichi
    Miyazawa, Teruomi
    REGENERATIVE MEDICINE, 2012, 7 (04) : 503 - 512
  • [17] PREDIFFERENTIATED AMNIOTIC FLUID MESENCHYMAL STEM CELLS ENHANCE REGENERATION OF LUNG TISSUES AND AMELIORATE ELASTASE-INDUCED PULMONARY EMPHYSEMA IN MICE MODEL
    Yen, Chih-Ching
    RESPIROLOGY, 2019, 24 : 169 - 170
  • [18] Changes to Platelet Phenotype Triggered by Elastase-Induced Lung Damage in a Murine Model of Emphysema
    Gustafsson, C.
    Amison, R. T.
    Page, C. P.
    Pitchford, S. C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2022, 205
  • [19] Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema
    Ying-Wei Lan
    Jing-Chan Yang
    Chih-Ching Yen
    Tsung-Teng Huang
    Ying-Cheng Chen
    Hsiao-Ling Chen
    Kowit-Yu Chong
    Chuan-Mu Chen
    Stem Cell Research & Therapy, 10
  • [20] Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema
    Lan, Ying-Wei
    Yang, Jing-Chan
    Yen, Chih-Ching
    Huang, Tsung-Teng
    Chen, Ying-Cheng
    Chen, Hsiao-Ling
    Chong, Kowit-Yu
    Chen, Chuan-Mu
    STEM CELL RESEARCH & THERAPY, 2019, 10 (1)
12345