Acute Liver Failure Caused by Secondary Hemophagocytic Lymphohistiocytosis After COVID-19 Vaccination-Case Report and Literature Review

被引：2

作者：

Premec, Hrvoje ^{[1
]}

Zivko, Matea ^{[2
]}

Mijic, Maja ^{[1
]}

Jelic-Puskaric, Biljana ^{[3
,4
]}

Lalovac, Milos ^{[1
,5
]}

Kanizaj, Tajana Filipec ^{[1
,2
]}

Sobocan, Nikola ^{[1
,2
]}

机构：

[1] Univ Hosp Merkur, Dept Gastroenterol, Zagreb, Croatia

[2] Univ Zagreb, Sch Med, Zagreb, Croatia

[3] Univ Hosp Merkur, Dept Pathol & Cytol, Zagreb, Croatia

[4] Catholic Univ Croatia, Sch Med, Zagreb, Croatia

[5] Univ Dubrovnik, Dubrovnik, Croatia

来源：

INTERNATIONAL MEDICAL CASE REPORTS JOURNAL | 2023年 / 16卷

关键词：

hemophagocytic lymphohistiocytosis; acute liver failure; COVID-19; vaccine; multisystem inflammatory syndrome; GUIDELINES; CHILDREN;

D O I：

10.2147/IMCRJ.S417347

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hemophagocytic lymphohistiocytosis (HLH) is a congenital or acquired hyperinflammatory syndrome, in some cases accompanied by acute liver failure. We present a case report of acute liver failure associated with HLH after COVID-19 vaccination and bring a literature review of the connection between HLH and COVID-19 vaccination. HLH has significant mortality rate, and liver transplantation is not a therapeutic option. Therefore, early recognition and timely conservative treatment are corner stones in reducing HLH-related morbidity and mortality.

引用

页码：449 / 455

页数：7

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