Acute Liver Failure Caused by Secondary Hemophagocytic Lymphohistiocytosis After COVID-19 Vaccination-Case Report and Literature Review

被引：2
|
作者：
Premec, Hrvoje [1 ]
Zivko, Matea [2 ]
Mijic, Maja [1 ]
Jelic-Puskaric, Biljana [3 ,4 ]
Lalovac, Milos [1 ,5 ]
Kanizaj, Tajana Filipec [1 ,2 ]
Sobocan, Nikola [1 ,2 ]
机构：
[1] Univ Hosp Merkur, Dept Gastroenterol, Zagreb, Croatia
[2] Univ Zagreb, Sch Med, Zagreb, Croatia
[3] Univ Hosp Merkur, Dept Pathol & Cytol, Zagreb, Croatia
[4] Catholic Univ Croatia, Sch Med, Zagreb, Croatia
[5] Univ Dubrovnik, Dubrovnik, Croatia
来源：
INTERNATIONAL MEDICAL CASE REPORTS JOURNAL | 2023年 / 16卷
关键词：
hemophagocytic lymphohistiocytosis; acute liver failure; COVID-19; vaccine; multisystem inflammatory syndrome; GUIDELINES; CHILDREN;
D O I：
10.2147/IMCRJ.S417347
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Hemophagocytic lymphohistiocytosis (HLH) is a congenital or acquired hyperinflammatory syndrome, in some cases accompanied by acute liver failure. We present a case report of acute liver failure associated with HLH after COVID-19 vaccination and bring a literature review of the connection between HLH and COVID-19 vaccination. HLH has significant mortality rate, and liver transplantation is not a therapeutic option. Therefore, early recognition and timely conservative treatment are corner stones in reducing HLH-related morbidity and mortality.
引用
收藏
页码：449 / 455
页数：7
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