Germ-free humanized mice reveal a crucial role for the gut microbiota in HIV and EBV pathogenesis

被引：0
|
作者：
Wahl, Angela [1 ]
Garcia, J. Victor [1 ]
机构：
[1] Univ N Carolina, Chapel Hill, NC 27599 USA
来源：
NATURE BIOTECHNOLOGY | 2024年 / 42卷 / 06期
关键词：
D O I：
10.1038/s41587-023-01908-3
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Directly analyzing the role of the gut microbiota during the course of infection with human-specific pathogens is not possible with existing methods. To overcome this problem, we developed a germ-free precision mouse model, which we used to compare the acquisition, replication and pathogenesis of HIV and Epstein-Barr virus.
引用
收藏
页码：854 / 855
页数：2
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