Germ-free humanized mice reveal a crucial role for the gut microbiota in HIV and EBV pathogenesis

被引：0

作者：

Wahl, Angela ^{[1
]}

Garcia, J. Victor ^{[1
]}

机构：

[1] Univ N Carolina, Chapel Hill, NC 27599 USA

来源：

NATURE BIOTECHNOLOGY | 2024年 / 42卷 / 06期

关键词：

D O I：

10.1038/s41587-023-01908-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Directly analyzing the role of the gut microbiota during the course of infection with human-specific pathogens is not possible with existing methods. To overcome this problem, we developed a germ-free precision mouse model, which we used to compare the acquisition, replication and pathogenesis of HIV and Epstein-Barr virus.

引用

页码：854 / 855

页数：2

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