Outcomes After Minimally Invasive Versus Open Total Pancreatectomy A Pan-European Propensity Score Matched Study

被引:10
|
作者
Scholten, Lianne [1 ]
Klompmaker, Sjors [1 ]
Van Hilst, Jony [1 ]
Annecchiarico, Mario M. [2 ]
Balzano, Gianpaolo [3 ]
Casadei, Riccardo [4 ]
Fabre, Jean-Michel [5 ]
Falconi, Massimo [3 ]
Ferrari, Giovanni [6 ]
Kerem, Mustafa [7 ]
Khatkov, Igor E. [8 ]
Lombardo, Carlo [9 ]
Manzoni, Alberto [10 ]
Mazzola, Michele [6 ]
Napoli, Niccolo [9 ]
Rosso, Edoardo E. [10 ]
Tyutyunnik, Pavel [8 ]
Wellner, Ulrich F. [11 ]
Fuks, David [12 ]
Burdio, Fernando [13 ]
Keck, Tobias [11 ]
Hilal, Mohammed Abu [10 ,14 ]
Besselink, Marc G. [1 ]
Boggi, Ugo [9 ]
机构
[1] Univ Amsterdam, Canc Ctr Amsterdam, Dept Surg, Amsterdam UMC, Amsterdam, Netherlands
[2] Careggi Univ Hosp, Dept Oncol & Robot Surg, Florence, Italy
[3] Osped San Raffaele, Sci Inst, Dept Pancreat Surg, Milan, Italy
[4] Univ Bologna, S Orsola Malpighi Hosp, DIMEC, Bologna, Italy
[5] CHU Montpellier, Dept Digest & Minimally Invas Oncol Surg, Montpellier, France
[6] ASST Grande Osped Metropolitano Niguarda, Dept Oncol & Mininvas Gen Surg, Milan, Italy
[7] Gazi Univ, Sch Med, Dept Gen Surg, Ankara, Turkiye
[8] Moscow Clin Sci Ctr, Dept Hightech Surg, Moscow, Russia
[9] Univ Pisa, Div Gen & Transplant Surg, Pisa, Italy
[10] Fdn Poliambulanza, Ist Ospedaliero, Dept Surg, Brescia, Italy
[11] UKSH, Dept Surg, Campus Lubeck, Lubeck, Germany
[12] Inst Mutualiste Montsouris, Dept Digest Oncol & Metab Surg, Paris, France
[13] Hosp Mar, Dept Surg, Barcelona, Spain
[14] Southampton Univ Hosp NHS Fdn Trust, Dept Surg, Southampton, England
关键词
laparoscopic surgery; minimally invasive surgery; pancreatic surgery; propensity score matching; robot-assisted surgery; total pancreatectomy; OPEN PANCREATICODUODENECTOMY; SURGERY; TUMORS;
D O I
10.1097/SLA.0000000000005075
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective:To assess postoperative 90-day outcomes after minimally invasive (laparoscopic/robot-assisted) total pancreatectomy (MITP) in selected patients versus open total pancreatectomy (OTP) among European centers. Background:Minimally invasive pancreatic surgery is becoming increasingly popular but data on MITP are scarce and multicenter studies comparing outcomes versus OTP are lacking. It therefore remains unclear if MITP is a valid alternative. Methods:Multicenter retrospective propensity-score matched study including consecutive adult patients undergoing MITP or OTP for all indications at 16 European centers in 7 countries (2008-2017). Patients after MITP were matched (1:1, caliper 0.02) to OTP controls. Missing data were imputed. The primary outcome was 90-day major morbidity (Clavien-Dindo >= 3a). Secondary outcomes included 90-day mortality, length of hospital stay, and survival. Results:Of 361 patients (99MITP/262 OTP), 70 MITP procedures (50 laparoscopic, 15 robotic, 5 hybrid) could be matched to 70 OTP controls. After matching, MITP was associated with a lower rate of major morbidity (17% MITP vs. 31% OTP, P = 0.022). The 90-day mortality (1.4% MITP vs. 7.1% OTP, P = 0.209) and median hospital stay (17 [IQR 11-24] MITP vs. 12 [10-23] days OTP, P = 0.876) did not differ significantly. Among 81 patients with PDAC, overall survival was 3.7 (IQR 1.7-N/A) versus 0.9 (IQR 0.5-N/ A) years, for MITP versus OTP, which was nonsignificant after stratification by T-stage. Conclusion:This international propensity score matched study showed that MITP may be a valuable alternative to OTP in selected patients, given the associated lower rate of major morbidity.
引用
收藏
页码:313 / 320
页数:8
相关论文
共 50 条
  • [21] Response: "A Propensity Score-matched Analysis of Open Versus Minimally Invasive Transthoracic Esophagectomy in the Netherlands''
    Seesing, Maarten F. J.
    Wijnhoven, Bas P. L.
    ANNALS OF SURGERY, 2018, 268 (06) : E75 - E76
  • [22] Outcomes after distal pancreatectomy for neuroendocrine neoplasms: a retrospective comparison between minimally invasive and open approach using propensity score weighting
    Stefano Partelli
    Valentina Andreasi
    Paola Maria Vittoria Rancoita
    Eduardo Perez-Sanchez
    Francesca Muffatti
    Gianpaolo Balzano
    Stefano Crippa
    Clelia Di Serio
    Massimo Falconi
    Surgical Endoscopy, 2021, 35 : 165 - 173
  • [23] Robot-assisted versus laparoscopic pancreatoduodenectomy: a pan-European multicenter propensity-matched study
    Emmen, Anouk M. L. H.
    Zwart, Maurice J. W.
    Khatkov, Igor E.
    Boggi, Ugo
    Koerkamp, Bas Groot
    Busch, Olivier R.
    Saint-Marc, Olivier
    Dokmak, Safi
    Molenaar, I. Quintus
    D'Hondt, Mathieu
    Ramera, Marco
    Keck, Tobias
    Ferrari, Giovanni
    Luyer, Misha D. P.
    Moraldi, Luca
    Ielpo, Benedetto
    Wittel, Uwe
    Souche, Francois-Regis
    Hackert, Thilo
    Lips, Daan
    Can, Mehmet Fatih
    Bosscha, Koop
    Fara, Regis
    Festen, Sebastiaan
    van Dieren, Susan
    Coratti, Andrea
    De Hingh, Ignace
    Mazzola, Michele
    Wellner, Ulrich
    De Meyere, Celine
    van Santvoort, Hjalmar C.
    Aussilhou, Beatrice
    Ibenkhayat, Abdallah
    de Wilde, Roeland F.
    Kauffmann, Emanuele F.
    Tyutyunnik, Pavel
    Besselink, Marc G.
    Abu Hilal, Mohammad
    SURGERY, 2024, 175 (06) : 1587 - 1594
  • [24] Outcomes after distal pancreatectomy for neuroendocrine neoplasms: a retrospective comparison between minimally invasive and open approach using propensity score weighting
    Partelli, Stefano
    Andreasi, Valentina
    Rancoita, Paola Maria Vittoria
    Perez-Sanchez, Eduardo
    Muffatti, Francesca
    Balzano, Gianpaolo
    Crippa, Stefano
    Di Serio, Clelia
    Falconi, Massimo
    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2021, 35 (01): : 165 - 173
  • [25] Outcomes of Open Versus Minimally Invasive Ivor-Lewis Esophagectomy for Cancer: A Propensity-Score Matched Analysis of NSQIP Database
    Naffouje, Samer A.
    Salloum, Rony H.
    Khalaf, Zaynab
    Salti, George I.
    ANNALS OF SURGICAL ONCOLOGY, 2019, 26 (07) : 2001 - 2010
  • [26] Outcomes of Open Versus Minimally Invasive Ivor-Lewis Esophagectomy for Cancer: A Propensity-Score Matched Analysis of NSQIP Database
    Samer A. Naffouje
    Rony H. Salloum
    Zaynab Khalaf
    George I. Salti
    Annals of Surgical Oncology, 2019, 26 : 2001 - 2010
  • [27] Predictors and outcomes of converted minimally invasive pancreaticoduodenectomy: a propensity score matched analysis
    Hester, Caitlin A.
    Nassour, Ibrahim
    Christie, Alana
    Augustine, Mathew M.
    Mansour, John C.
    Polanco, Patricio M.
    Porembka, Matthew R.
    Shoultz, Thomas H.
    Wang, Sam C.
    Yopp, Adam C.
    Zeh, Herbert J., III
    Minter, Rebecca M.
    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2020, 34 (02): : 544 - 550
  • [28] Predictors and outcomes of converted minimally invasive pancreaticoduodenectomy: a propensity score matched analysis
    Caitlin A. Hester
    Ibrahim Nassour
    Alana Christie
    Mathew M. Augustine
    John C. Mansour
    Patricio M. Polanco
    Matthew R. Porembka
    Thomas H. Shoultz
    Sam C. Wang
    Adam C. Yopp
    Herbert J. Zeh
    Rebecca M. Minter
    Surgical Endoscopy, 2020, 34 : 544 - 550
  • [29] Robotic versus standard open pancreatectomy: a propensity score-matched analysis comparison
    Benedetto Ielpo
    Riccardo Caruso
    Hipolito Duran
    Eduardo Diaz
    Isabel Fabra
    Luis Malavé
    Yolanda Quijano
    Emilio Vicente
    Updates in Surgery, 2019, 71 : 137 - 144
  • [30] Minimally invasive versus open liver resection for hepatocellular carcinoma in the elderly: international multicentre propensity score-matched study
    Sijberden, Jasper P.
    Cipriani, Federica
    Lanari, Jacopo
    Russolillo, Nadia
    Cacciaguerra, Andrea Benedetti
    Osei-Bordom, Daniel
    Conci, Simone
    Gorgec, Burak
    Primrose, John N.
    Edwin, Bjorn
    Lopez-Ben, Santi
    D'Hondt, Mathieu
    Rotellar, Fernando
    Besselink, Marc G.
    Dagher, Ibrahim
    Giuliante, Felice
    Fuks, David
    Rozzini, Renzo
    Ruzzenente, Andrea
    Sutcliffe, Robert P.
    Vivarelli, Marco
    Ferrero, Alessandro
    Cillo, Umberto
    Aldrighetti, Luca A.
    Abu Hilal, Mohammad
    BRITISH JOURNAL OF SURGERY, 2023, 110 (08) : 927 - 930