Improving stem cell-derived pancreatic islets using single-cell multi-inferred regulomes

被引：0

作者：

de Celis, Maria F. Rubin ^{[1
,2
]}

Bonner-Weir, Susan ^{[3
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Div Endocrinol Diabet & Metab, Dept Med, Boston, MA 02215 USA

[2] Harvard Med Sch, Boston, MA 02215 USA

[3] Harvard Med Sch, Joslin Diabet Ctr, Boston, MA 02215 USA

来源：

DEVELOPMENTAL CELL | 2023年 / 58卷 / 09期

关键词：

IN-VITRO;

D O I：

10.1016/j.devcel.2023.04.008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In this issue of Developmental Cell, Zhu et al. provide integrated data from single-cell/nuclei RNAseq and chromatin accessibility (ATAC) across both a multistaged differentiation protocol-deriving pancreatic islets from hESCs and primary islets. This important resource could be leveraged for optimizing the differentiation and maturation of pancreatic islet cells from hESCs.

引用

页码：725 / 726

页数：2

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