Improving stem cell-derived pancreatic islets using single-cell multi-inferred regulomes

被引：0
|
作者：
de Celis, Maria F. Rubin [1 ,2 ]
Bonner-Weir, Susan [3 ]
机构：
[1] Beth Israel Deaconess Med Ctr, Div Endocrinol Diabet & Metab, Dept Med, Boston, MA 02215 USA
[2] Harvard Med Sch, Boston, MA 02215 USA
[3] Harvard Med Sch, Joslin Diabet Ctr, Boston, MA 02215 USA
来源：
DEVELOPMENTAL CELL | 2023年 / 58卷 / 09期
关键词：
IN-VITRO;
D O I：
10.1016/j.devcel.2023.04.008
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In this issue of Developmental Cell, Zhu et al. provide integrated data from single-cell/nuclei RNAseq and chromatin accessibility (ATAC) across both a multistaged differentiation protocol-deriving pancreatic islets from hESCs and primary islets. This important resource could be leveraged for optimizing the differentiation and maturation of pancreatic islet cells from hESCs.
引用
收藏
页码：725 / 726
页数：2
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