Serum and Urethral Antibody Response in Mycoplasma genitalium-Infected Men

被引:1
|
作者
Kim, Caroline M. [1 ]
Manhart, Lisa E. [2 ,3 ]
Wood, Gwendolyn E. [1 ,4 ]
机构
[1] Univ Washington, Dept Med, Div Allergy & Infect Dis, Seattle, WA USA
[2] Univ Washington, Ctr AIDS & STD, Seattle, WA USA
[3] Univ Washington, Dept Epidemiol, Seattle, WA USA
[4] Univ Washington, Dept Med, Div Allergy & Infect Dis, 325 Ninth Ave,Box 359779, Seattle, WA 98104 USA
基金
美国国家卫生研究院;
关键词
RECOMBINATION; MGPB;
D O I
10.1097/OLQ.0000000000001845
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The antibody response to Mycoplasma genitalium in serum and urethral secretions of men with nongonococcal urethritis was examined longitudinally. Serum and urethral antibodies reacted primarily with the MgpB and MgpC adhesins. Serum antibodies persisted throughout follow-up, whereas urethral antibodies waned despite organism persistence. Declining antibodies may facilitate chronic infection.
引用
收藏
页码:E26 / E29
页数:4
相关论文
共 50 条
  • [21] Mycoplasma genitalium infection and host antibody immune response in patients infected by HIV, patients attending STD clinics and in healthy blood donors
    Wang, RYH
    Grandinetti, T
    Shih, JWK
    Weiss, SH
    Haley, CLD
    Hayes, MM
    Lo, SC
    FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 1997, 19 (03): : 237 - 245
  • [22] The spread of Mycoplasma genitalium among men who have sex with men
    Edlund, M.
    Blaxhult, A.
    Bratt, G.
    INTERNATIONAL JOURNAL OF STD & AIDS, 2012, 23 (06) : 455 - 456
  • [23] Mycoplasma genitalium: An emerging superbug among men having sex with men
    Juyal, Deepak
    Sethi, Sunil
    Dhawan, Neha
    Gupta, Somesh
    Dhawan, Benu
    INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2025, 91 (01): : 136 - 137
  • [24] MICROIMMUNOFLUORESCENCE TECHNIQUE FOR DETECTION OF ANTIBODY TO MYCOPLASMA-GENITALIUM
    FURR, PM
    TAYLORROBINSON, D
    JOURNAL OF CLINICAL PATHOLOGY, 1984, 37 (09) : 1072 - 1074
  • [25] Association of Mycoplasma genitalium with nongonococcal urethritis in heterosexual men
    Totten, PA
    Schwartz, MA
    Sjöström, KE
    Kenny, GE
    Handsfield, HH
    Weiss, JB
    Whittington, WLH
    JOURNAL OF INFECTIOUS DISEASES, 2001, 183 (02): : 269 - 276
  • [26] URETHRAL INFECTION IN MALE CHIMPANZEES PRODUCED EXPERIMENTALLY BY MYCOPLASMA-GENITALIUM
    TAYLORROBINSON, D
    TULLY, JG
    BARILE, MF
    BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY, 1985, 66 (01): : 95 - 101
  • [27] Sitafloxacin Therapy for Mycoplasma Genitalium in Men who have Sex with Men
    Ando, N.
    Mizushima, D.
    Takano, M.
    Aoki, T.
    Yanagawa, Y.
    Watanabe, K.
    Uemura, H.
    Mitobe, M.
    Kobayashi, K.
    Kubota, H.
    Miyake, H.
    Shinkai, T.
    Sadamasu, K.
    Gatanaga, H.
    Oka, S.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2022, 25 : 75 - 75
  • [28] Mycoplasma genitalium membrane lipoprotein induces GAPDH malonylation in urethral epithelial cells to regulate cytokine response
    Wang, Xiaoliu
    Hu, Yi
    Li, Xinru
    Huang, Liubin
    Yang, Yan
    Liu, Chang
    Deng, Qing
    Yang, Pei
    Li, Yilin
    Zhou, Yiwen
    Xiao, Lihua
    Wu, Haiying
    He, Lu
    MICROBIAL PATHOGENESIS, 2024, 195
  • [29] Developing a Public Health Response to Mycoplasma genitalium
    Golden, Matthew R.
    Workowski, Kimberly A.
    Bolan, Gail
    JOURNAL OF INFECTIOUS DISEASES, 2017, 216 : S420 - S426
  • [30] Transcriptional response of Mycoplasma genitalium to osmotic stress
    Zhang, Wenbo
    Baseman, Joel B.
    MICROBIOLOGY-SGM, 2011, 157 : 548 - 556