Dimethyl fumarate inhibits necroptosis and alleviates systemic inflammatory response syndrome by blocking the RIPK1-RIPK3-MLKL axis

被引:0
|
作者
Khanpour, M. Amin [1 ,2 ]
Moradiani, Fatemeh [2 ]
Parsanasab, Gholam-Mohammad [2 ]
Karimzadeh, R. [1 ]
机构
[1] Shahid Beheshti Univ, Dept Phys, Tehran 19839, Iran
[2] Shahid Beheshti Univ, Fac Elect Engn, Integrated Photon Lab, Tehran 1983963113, Iran
来源
OPTICS AND LASER TECHNOLOGY | 2023年 / 162卷
关键词
Micro-cavity; Plasmonic; Purcell factor; Mode volume; SURFACE-PLASMON RESONANCE; WHISPERING-GALLERY MODE; THEORETICAL-ANALYSIS; CAVITY;
D O I
10.1016/j.optlastec.2023.109236
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Geometrical parameters of coupled plasmonic resonators that consist of micro-disk and micro-ring structures have been investigated numerically, and changes in the Q factor, mode volume, and Purcell coefficient of the investigated structure have been calculated according to changes in geometrical variables. Optimal geometrical values for achieving plasmonic modes have been found using simulation results. Additionally, the performance of a single micro-disk, the single micro-ring, and two coupled micro-ring structures as a refractive index sensor has been compared and reported. It has also been shown that although the general shape of the figure of merit (FoM) graph is the same for all tested structures, the FoM of the disk resonator achieves lower values compared to ring and coupled resonators.
引用
收藏
页数:9
相关论文
共 50 条
  • [21] Protective effect of astaxanthin against SnS2 nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice
    Yuan, Lu
    Liang, Peng
    Qu, Yunhua
    An, Tianyang
    Wang, Jianhui
    Deng, Xuenan
    Bai, Liyuan
    Shen, Peijun
    Bai, Disi
    FOOD AND CHEMICAL TOXICOLOGY, 2020, 145
  • [22] RETRA induces necroptosis in cervical cancer cells through RIPK1, RIPK3, MLKL and increased ROS production
    Mohanty, Suchitra
    Yadav, Poonam
    Lakshminarayanan, Harini
    Sharma, Priyanshu
    Vivekanandhan, Aravindhan
    Karunagaran, Devarajan
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2022, 920
  • [23] Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL
    ZHANG Yi-yue
    LIU Wei-ning
    LI Yue-qi
    LUO Xiu-ju
    PENG Jun
    中国药理学与毒理学杂志, 2019, 33 (09) : 703 - 703
  • [24] Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway
    Zhang, Yi-Yue
    Liu, Wei-Ning
    Li, Yue-Qi
    Zhang, Xiao-Jie
    Yang, Jie
    Luo, Xiu-Ju
    Peng, Jun
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2019, 392 (09) : 1085 - 1095
  • [25] Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway
    Yi-Yue Zhang
    Wei-Ning Liu
    Yue-Qi Li
    Xiao-Jie Zhang
    Jie Yang
    Xiu-Ju Luo
    Jun Peng
    Naunyn-Schmiedeberg's Archives of Pharmacology, 2019, 392 : 1085 - 1095
  • [26] UVB-Induced necroptosis of the skin cells via RIPK3-MLKL activation independent of RIPK1 kinase activity
    Tairan Hu
    Xiaodong Lai
    Li Li
    Yi Li
    Meng Wang
    Haini Zhang
    Yan Yang
    Chong Zhang
    Yan Yan
    Baoxi Wang
    Cell Death Discovery, 11 (1)
  • [27] Necrostatin-1 Prevents Necroptosis in Brains after Ischemic Stroke via Inhibition of RIPK1-Mediated RIPK3/MLKL Signaling
    Deng, Xu-Xu
    Li, Shan-Shan
    Sun, Feng-Yan
    AGING AND DISEASE, 2019, 10 (04): : 807 - 817
  • [28] RIPK1/RIPK3/MLKL-mediated necroptosis contributes to compression-induced rat nucleus pulposus cells death
    Songfeng Chen
    Xiao Lv
    Binwu Hu
    Zengwu Shao
    Baichuan Wang
    Kaige Ma
    Hui Lin
    Min Cui
    Apoptosis, 2017, 22 : 626 - 638
  • [29] The Trend of ripk1/ripk3 and mlkl Mediated Necroptosis Pathway in Patients with Different Stages of Prostate Cancer as Promising Progression Biomarkers
    Heidaryan, Farnaz
    Bamehr, Hadi
    Babaabasi, Babak
    Imamverdi, Alireza
    Mohammadzadeh, Nima
    Khalili, Ahmad
    CLINICAL LABORATORY, 2020, 66 (03) : 249 - 254
  • [30] RIPK1/RIPK3/MLKL-mediated necroptosis contributes to compression-induced rat nucleus pulposus cells death
    Chen, Songfeng
    Lv, Xiao
    Hu, Binwu
    Shao, Zengwu
    Wang, Baichuan
    Ma, Kaige
    Lin, Hui
    Cui, Min
    APOPTOSIS, 2017, 22 (05) : 626 - 638