PurposeWe explore the choroid vasculature changes of acute Vogt-Koyanagi-Harada (VKH) disease using widefield optical coherence tomography angiography (OCTA).MethodsIn this retrospective, observational, longitudinal study, 16 patients with acute VKH disease (32 eyes, mean age: 42.19 +/- 13.66 years) were measured using widefield OCTA.ResultsIn this study, we first described the multiple dark foci in choriocapillaris and Sattler's layer in the panoramic montage of the five 12x12mm images in 30 eyes (93.8%) of acute VKH disease. OCTA follow-up in these 30 eyes demonstrated the diminished size and number of these dark foci in choriocapillaris and Sattler's layer after the initiation of treatment.ConclusionsWidefield OCTA enables noninvasive identification of characteristics of flow void at the level of superficial choroidal vessels in the acute phase and may be a novel valuable tool for diagnosis and monitoring of disease progression in VKH disease in the future.
机构:
Eye Protect Fdn Bayrampasa Eye Hosp, Istanbul, Turkiye
Istanbul Univ, Istanbul Fac Med, Dept Ophthalmol, Istanbul, TurkiyeEye Protect Fdn Bayrampasa Eye Hosp, Istanbul, Turkiye
Tugal-Tutkun, Ilknur
Smit, Derrick P.
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Stellenbosch Univ, Fac Med & Hlth Sci, Div Ophthalmol, Cape Town, South AfricaEye Protect Fdn Bayrampasa Eye Hosp, Istanbul, Turkiye
Smit, Derrick P.
Abu El-Asrar, Ahmed M.
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King Saud Univ, Coll Med, Dept Ophthalmol, Riyadh, Saudi Arabia
King Saud Univ, Coll Med, Dr Nasser Al Rashid Res Chair Ophthalmol, Riyadh, Saudi ArabiaEye Protect Fdn Bayrampasa Eye Hosp, Istanbul, Turkiye
机构:
Grp Hosp Cochin, Ctr Cochin Ambulatoire Ophtalmol, Hotel Dieu, 27 Rue Faubourg St Jacques, F-75014 Paris, FranceUniv Paris 05, F-75014 Paris, France
Daudin, J. -B.
Monnet, D.
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Univ Paris 05, F-75014 Paris, France
Grp Hosp Cochin, Ctr Cochin Ambulatoire Ophtalmol, Hotel Dieu, 27 Rue Faubourg St Jacques, F-75014 Paris, FranceUniv Paris 05, F-75014 Paris, France
Monnet, D.
Brezin, A.
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Univ Paris 05, F-75014 Paris, France
Grp Hosp Cochin, Ctr Cochin Ambulatoire Ophtalmol, Hotel Dieu, 27 Rue Faubourg St Jacques, F-75014 Paris, FranceUniv Paris 05, F-75014 Paris, France