Iron-laden blasts in refractory acute myeloid leukemia

被引：0
|
作者：
Vossen, Christopher [1 ]
Im, Roeun [1 ]
Horna, Pedro [1 ]
机构：
[1] Mayo Clin, Dept Lab Med & Pathol, Div Hematopathol, 200 1st St SW, Rochester, MN 55905 USA
来源：
JOURNAL OF HEMATOPATHOLOGY | 2023年 / 16卷 / 03期
关键词：
Acute myeloid leukemia; Green cytoplasmic granules; Hemosiderin-laden blasts;
D O I：
10.1007/s12308-023-00555-6
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a case of refractory acute myeloid leukemia with DEK-NUP214 rearrangement showing circulating monocytic blasts with abundant green cytoplasmic granules on the Wright-Giemsa stain. The granules were strongly positive for Perls' Prussian blue, consistent with hemosiderin deposits. This previously unreported finding is suggestive of siderophage activity by leukemic blasts, likely associated with monocytic differentiation.
引用
收藏
页码：187 / 188
页数：2
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