Genome-wide DNA methylation profiling in chronic lymphocytic leukaemia

被引:0
|
作者
Barreyat, Marylis [1 ]
Chambon, Philippe [1 ]
Mahfouf, Jean-Francois [1 ]
Faure, Ghislain [1 ]
机构
[1] Univ Toulouse, CNRM, Meteo France, CNRS, Toulouse, France
来源
ATMOSPHERIC SCIENCE LETTERS | 2023年 / 24卷 / 03期
关键词
cloud; hydrometeors; microwave; snow; SINGLE-SCATTERING PROPERTIES; RADAR REFLECTIVITY DATA; MICROWAVE OBSERVATIONS; FROZEN HYDROMETEORS; OPERATIONAL IMPLEMENTATION; RADIATIVE-TRANSFER; ICE; ASSIMILATION; MODEL; TEMPERATURE;
D O I
10.1002/asl.1142
中图分类号
P3 [地球物理学]; P59 [地球化学];
学科分类号
0708 ; 070902 ;
摘要
Numerical weather prediction centers increasingly make use of cloudy and rainy microwave radiances. Currently, the high microwave frequencies are simulated using simplified assumptions regarding the radiative properties of frozen hydrometeors. In particular, one single particle shape is often used for all precipitating frozen particles, all over the globe, and for all cloud types. In this paper, a multi-SSP (single scattering properties) approach for 1D Bayesian inversions is examined. Two experiments were set up: (1) one with three SSPs and (2) one with the previous SSPs plus one which leads to very cold brightness temperature distributions. For that purpose, we used observations from the GPM Microwave Imager radiometer over 2 months period and forecasts from the Meteo-France convective scale AROME model. The results showed that mixtures of SSP are chosen by the inversion method for meteorological conditions with low scattering and that a single particle is chosen for those with high scattering to perform the inversions. Despite the fact that no specific weather scenes were found to be associated with a particular SSP the most efficient scattering particles can be favored for some of them.
引用
收藏
页数:11
相关论文
共 50 条
  • [21] Genome-wide DNA methylation in chronic heart disease
    Gilsbach, R.
    Preissl, S.
    Ruehle, F.
    Weiss, S.
    Muehle, A.
    Doenst, T.
    Stoll, M.
    Hein, L.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2012, 385 : 29 - 29
  • [22] Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia
    Pei, Lirong
    Choi, Jeong-Hyeon
    Liu, Jimei
    Lee, Eun-Joon
    McCarthy, Brian
    Wilson, James M.
    Speir, Ethan
    Awan, Farrukh
    Tae, Hongseok
    Arthur, Gerald
    Schnabel, Jennifer L.
    Taylor, Kristen H.
    Wang, Xinguo
    Xu, Dong
    Ding, Han-Fei
    Munn, David H.
    Caldwell, Charles W.
    Shi, Huidong
    EPIGENETICS, 2012, 7 (06) : 567 - 578
  • [23] GENOME-WIDE METHYLATION PROFILING OF SCHIZOPHRENIA
    Rukova, B.
    Staneva, R.
    Hadjidekova, S.
    Stamenov, G.
    Milanova, V
    Toncheva, D.
    BALKAN JOURNAL OF MEDICAL GENETICS, 2014, 17 (02) : 15 - 23
  • [24] Genome-wide high resolution DNA profiling of hairy cell leukaemia
    Rinaldi, Andrea
    Kwee, Ivo
    Young, Ken H.
    Zucca, Emanuele
    Gaidano, Gianluca
    Forconi, Francesco
    Bertoni, Francesco
    BRITISH JOURNAL OF HAEMATOLOGY, 2013, 162 (04) : 566 - 569
  • [25] Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia
    Rani, Lata
    Mathur, Nitin
    Gupta, Ritu
    Gogia, Ajay
    Kaur, Gurvinder
    Dhanjal, Jaspreet Kaur
    Sundar, Durai
    Kumar, Lalit
    Sharma, Atul
    CLINICAL EPIGENETICS, 2017, 9
  • [26] Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia
    Lata Rani
    Nitin Mathur
    Ritu Gupta
    Ajay Gogia
    Gurvinder Kaur
    Jaspreet Kaur Dhanjal
    Durai Sundar
    Lalit Kumar
    Atul Sharma
    Clinical Epigenetics, 2017, 9
  • [27] Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia
    Sandoval, Juan
    Heyn, Holger
    Mendez-Gonzalez, Jesus
    Gomez, Antonio
    Moran, Sebastian
    Baiget, Montserrat
    Melo, Montserrat
    Badell, Isabel
    Nomdedeu, Josep F.
    Esteller, Manel
    BRITISH JOURNAL OF HAEMATOLOGY, 2013, 160 (03) : 406 - 409
  • [28] Genome-wide DNA methylation profiling in tongue squamous cell carcinoma
    Rapado-Gonzalez, Oscar
    Costa-Fraga, Nicolas
    Bao-Caamano, Aida
    Lopez-Cedrun, Jose Luis
    Alvarez-Rodriguez, Roberto
    Crujeiras, Ana Belen
    Muinelo-Romay, Laura
    Lopez-Lopez, Rafael
    Diaz-Lagares, Angel
    Mercedes Suarez-Cunqueiro, Maria
    ORAL DISEASES, 2024, 30 (02) : 259 - 271
  • [29] Genome-Wide Profiling of Ageing Associated DNA Methylation in Healthy Population
    Noreen, Faiza
    Schaer, Primo
    Truninger, Kaspar
    SWISS MEDICAL WEEKLY, 2011, 141 : 13S - 13S
  • [30] Genome-Wide DNA Methylation Profiling of Sporadic and Familial Colorectal Cancer
    Milewski, M. A.
    Leahy, D. T.
    Conroy, J.
    Ennis, S.
    Mulcahy, H.
    Hyland, J.
    O'Donoghue, D.
    Sheahan, K.
    LABORATORY INVESTIGATION, 2010, 90 : 156A - 156A