Copy number variants of ERG11: mechanism of azole resistance in Candida parapsilosis

被引:3
|
作者
Ning, Yating [1 ,2 ]
Dai, Rongchen [1 ,2 ]
Zhang, Li [2 ]
Xu, Yingchun [1 ,2 ]
Xiao, Meng [1 ,2 ]
机构
[1] Chinese Acad Med Sci, Peking Union Med Coll Hosp, State Key Lab Complex Severe & Rare Dis, Dept Lab Med, Beijing 100730, Peoples R China
[2] Beijing Key Lab Mech Res & Precis Diag Invas Funga, Beijing, Peoples R China
来源
LANCET MICROBE | 2024年 / 5卷 / 01期
关键词
D O I
10.1016/S2666-5247(23)00294-X
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
引用
收藏
页码:E10 / E10
页数:1
相关论文
共 50 条
  • [41] The heme-binding protein Dap1 links iron homeostasis to azole resistance via the P450 protein Erg11 in Candida glabrata
    Hosogaya, Naoki
    Miyazaki, Taiga
    Nagi, Minoru
    Tanabe, Koichi
    Minematsu, Asuka
    Nagayoshi, Yohsuke
    Yamauchi, Shunsuke
    Nakamura, Shigeki
    Imamura, Yoshifumi
    Izumikawa, Koichi
    Kakeya, Hiroshi
    Yanagihara, Katsunori
    Miyazaki, Yoshitsugu
    Kugiyama, Kiyotaka
    Kohno, Shigeru
    [J]. FEMS YEAST RESEARCH, 2013, 13 (04) : 411 - 421
  • [42] Susceptibility of clinical isolates of Candida species to fluconazole and detection of Candida albicans ERG11 mutations
    Xu, Yonghao
    Chen, Lamei
    Li, Chunyang
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 61 (04) : 798 - 804
  • [43] Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature
    Morio, Florent
    Loge, Cedric
    Besse, Bernard
    Hennequin, Christophe
    Le Pape, Patrice
    [J]. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2010, 66 (04) : 373 - 384
  • [44] Recurrent copy number variations in the human fungal pathogen Candida parapsilosis
    Selmecki, Anna
    [J]. MBIO, 2023, 14 (05):
  • [45] The A395T Mutation in ERG11 Gene Confers Fluconazole Resistance in Candida tropicalis Causing Candidemia
    Jingwen Tan
    Jinqing Zhang
    Wei Chen
    Yi Sun
    Zhe Wan
    Ruoyu Li
    Wei Liu
    [J]. Mycopathologia, 2015, 179 : 213 - 218
  • [46] Analysis of clinical Candida parapsilosis isolates reveals copy number variation in key fluconazole resistance genes
    Bergin, Sean
    Doorley, Laura A.
    Rybak, Jeffrey M.
    Wolfe, Kenneth H.
    Butler, Geraldine
    Cuomo, Christina A.
    Rogers, P. David
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2024,
  • [47] The A395T Mutation in ERG11 Gene Confers Fluconazole Resistance in Candida tropicalis Causing Candidemia
    Tan, Jingwen
    Zhang, Jinqing
    Chen, Wei
    Sun, Yi
    Wan, Zhe
    Li, Ruoyu
    Liu, Wei
    [J]. MYCOPATHOLOGIA, 2015, 179 (3-4) : 213 - 218
  • [48] In vitro and in vivo effects of 14α-demethylase (ERG11) depletion in Candida glabrata
    Nakayama, H
    Nakayama, N
    Arisawa, M
    Aoki, Y
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (11) : 3037 - 3045
  • [49] Is the S405F mutation in Candida albicans ERG11 gene sufficient to confer resistance to fluconazole?
    Oliveira-Carvalho, V.
    Del Negro, G. M. B.
    [J]. JOURNAL DE MYCOLOGIE MEDICALE, 2014, 24 (03): : 241 - 242
  • [50] Detection of erg11 gene mutation in fluconazole resistant Candida albicans isolates
    Sheena, M. S.
    Singh, Rakesh
    [J]. MEDICAL MYCOLOGY, 2022, 60 (SUPP 1): : 255 - 255