Kidney Organ Allocation System: How to Be Fair

被引:7
|
作者
Yeung, Melissa Y. [1 ,2 ,7 ]
Coates, P. Toby [3 ,4 ]
Li, Philip Kam-Tao [5 ,6 ,8 ,9 ]
机构
[1] Brigham & Womens Hosp, Dept Med, Renal Div, Boston, MA 02115 USA
[2] Harvard Med Sch, Boston, MA USA
[3] Univ Adelaide, Royal Adelaide Hosp, Kidney & Pancreat Islet Transplantat, Adelaide, SA 5000, Australia
[4] Univ Adelaide, Royal Adelaide Hosp, Med, Adelaide, SA 5000, Australia
[5] Prince Wales Hosp, Dept Med & Therapeut, Shatin, Hong Kong, Peoples R China
[6] Chinese Univ Hong Kong, Carol & Richard Yu PD Res Ctr, Hong Kong, Peoples R China
[7] Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA
[8] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Hong Kong, Peoples R China
[9] Chinese Univ Hong Kong, Prince Wales Hosp, Carol & Richard Yu PD Res Ctr, Hong Kong, Peoples R China
关键词
Kidney transplant; organ allocation; transplant; ethics of organ allocation; DECEASED DONOR KIDNEYS; HLA-B; TRANSPLANTATION; HEALTH; DIALYSIS; DISPARITIES; PRINCIPLES; A(2)/A(2)B; EFFICIENCY; EQUITY;
D O I
10.1016/j.semnephrol.2022.09.002
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Transplantation is a life-saving medical intervention that unfortunately is constrained by scarcity of available organs. An ideal system for allocating organs should seek to achieve the greatest good for the greatest number of people. It also must be fair and not disadvantage certain populations. However, policies aimed at reducing disparities also must be balanced with considerations of utility (graft outcomes), cost, efficiency, and any adverse effects on organ utilization. Here, we discuss the ethical challenges of creating a fair and equitable organ allocation system, focusing on the principles governing deceased donor kidney transplant waitlists around the world. The kidney organ allocation systems in the United States, Australia, and Hong Kong are used as illustrations. (c) 2023 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
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页数:16
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