Effects of L-Glutamine on Biomarkers of Response in Sickle Cell Disease: A Pharmacokinetics-Pharmacodynamics Analysis

被引:1
|
作者
Sadaf, Alina [1 ]
Dong, Min [2 ]
Korpik, Jennifer [1 ]
Pfeiffer, Amanda [1 ]
Kalfa, Theodosia A. [3 ]
Latham, Teresa S. [1 ]
Vinks, Alexander A. [2 ]
Ware, Russell E. [1 ]
Quinn, Charles T. [1 ]
机构
[1] Cincinnati Childrens Hosp Med Ctr, Div Hematol, Cincinnati, OH USA
[2] Cincinnati Childrens Hosp Med Ctr, Div Clin Pharmacol, Cincinnati, OH USA
[3] Cincinnati Childrens Hosp Med Ctr, Canc & Blood Dis Inst, Cincinnati, OH USA
关键词
D O I
10.1182/blood-2023-180312
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [21] L-glutamine use in adults with sickle cell disease: Clinical trials where success meets reality
    Ogu, Ugochi O.
    Thomas, Merin
    Chan, Florence
    Vattappally, Leena
    Sebastian, Gracy
    Crouch, Andrew
    You, Shuo
    Minniti, Caterina P.
    AMERICAN JOURNAL OF HEMATOLOGY, 2021, 96 (01) : E38 - E40
  • [22] The Evaluation of Transfusion Data from the Phase 3 Clinical Study of L-Glutamine in Sickle Cell Disease
    Lam, Hung
    Becerra, Joseph M.
    Stark, Charles W.
    Niihara, Yutaka
    Callaghan, Michael
    BLOOD, 2021, 138
  • [23] Pediatric Patients with Sickle Cell Disease at Harbor-UCLA & Early Experience of L-Glutamine Therapy
    Gotesman, Moran
    Elgar, Guy
    Pak, Youngju
    Santiago, Laura Hernandez
    Alvarez, Abigail
    Lin, Henry
    Lasky, Joseph L., III
    Panosyan, Eduard H.
    BLOOD, 2020, 136
  • [24] L-Glutamine Decreases Opioid Use in Individuals with Sickle Cell Disease and Chronic Pain: A Case Series
    Wilson, Samuel
    Wright, Frances
    Carden, Marcus A.
    BLOOD, 2019, 134
  • [25] L-glutamine therapy improves minute ventilation of sickle cell anemia patients
    Macan, Henry R.
    Porszasz, Janos
    Tsurugaya, Hideki
    Razon, Rafael L.
    Koh, Han
    Casaburi, Richard
    Tanaka, Kouichi R.
    Niihara, Yutaka
    BLOOD, 2007, 110 (11) : 13B - 13B
  • [26] Population Pharmacokinetics/Pharmacodynamics of Ticagrelor in Children with Sickle Cell Disease
    Amilon, Carl
    Niazi, Mohammad
    Berggren, Anders
    Astrand, Magnus
    Hamren, Bengt
    CLINICAL PHARMACOKINETICS, 2019, 58 (10) : 1295 - 1307
  • [27] Population Pharmacokinetics/Pharmacodynamics of Ticagrelor in Children with Sickle Cell Disease
    Carl Amilon
    Mohammad Niazi
    Anders Berggren
    Magnus Åstrand
    Bengt Hamrén
    Clinical Pharmacokinetics, 2019, 58 : 1295 - 1307
  • [28] Evaluation of Dosage and Food Effect on L-Glutamine Exposure for Sickle Cell Anemia: A Population Pharmacokinetic Analysis
    Dong, Min
    Sadaf, Alina
    Vinks, Alexander A.
    Ware, Russell E.
    Quinn, Charles T.
    BLOOD, 2022, 140 : 8256 - 8257
  • [29] Pharmacokinetics of L-Glutamine (Endari) in Pediatric and Adult Sickle Cell Disease Patients: A Phase 4, Open-Label, Single-Center Study
    Sadaf, Alina
    Dong, Min
    Pfeiffer, Amanda
    Latham, Teresa
    Vinks, Alexander A.
    Ware, Russell E.
    Quinn, Charles T.
    BLOOD, 2021, 138
  • [30] A Phase 3 Study of L-Glutamine Therapy for Sickle Cell Anemia and Sickle β0-Thalassemia
    Niihara, Yutaka
    Koh, Han A.
    Tran, Lan
    Razon, Rafael
    Macan, Henry
    Stark, Charles
    Wun, Ted
    Adams-Graves, Patricia
    BLOOD, 2014, 124 (21)