Combining atomic force microscopy with complementary techniques for multidimensional single-cell analysis

被引:7
|
作者
Li, Mi [1 ,2 ,3 ]
机构
[1] Chinese Acad Sci, Shenyang Inst Automat, State Key Lab Robot, Shenyang 110016, Peoples R China
[2] Chinese Acad Sci, Inst Robot & Intelligent Mfg, Shenyang, Peoples R China
[3] Univ Chinese Acad Sci, Beijing, Peoples R China
基金
中国国家自然科学基金;
关键词
atomic force microscopy; fluidic force microscopy; infrared spectroscopy; scanning near-field ultrasound holography; single-cell analysis; tip-enhanced Raman scattering; traction force microscopy; ENHANCED RAMAN-SPECTROSCOPY; LIVING CELLS; SUPERRESOLUTION MICROSCOPY; LIGHT-MICROSCOPY; HETEROGENEITY; AFM; CANCER; MECHANICS; STIFFNESS; PROTEINS;
D O I
10.1111/jmi.13183
中图分类号
TH742 [显微镜];
学科分类号
摘要
The advent of atomic force microscopy (AFM) provides an amazing instrument for characterising the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution. In addition to its own unique capabilities for applications in life sciences, AFM is highly compatible and has been widely integrated with various complementary techniques to simultaneously sense the multidimensional (biological, chemical and physical) properties of biological systems, offering novel possibilities for comprehensively revealing the underlying mechanisms guiding life activities particularly in the studies of single cells. Herein, typical combinations of AFM and complementary techniques (including optical microscopy, ultrasound, infrared spectroscopy, Raman spectroscopy, fluidic force microscopy and traction force microscopy) and their applications in single-cell analysis are reviewed. The future perspectives are also provided.
引用
收藏
页码:69 / 96
页数:28
相关论文
共 50 条
  • [21] Combining confocal and atomic force microscopy to quantify single-virus binding to mammalian cell surfaces
    Newton, Richard
    Delguste, Martin
    Koehler, Melanie
    Dumitru, Andra C.
    Laskowski, Pawel R.
    Mueller, Daniel J.
    Alsteens, David
    NATURE PROTOCOLS, 2017, 12 (11) : 2275 - 2292
  • [22] Atomic force microscopy in a liquid and in situ ellipsometry as complementary techniques for the study of protein adsorption
    Almeida, AT
    Gliemann, H
    Schimmel, T
    Petri, DFS
    SURFACE AND COLLOID SCIENCE, 2004, 128 : 63 - 67
  • [23] Probing bacterial interactions: integrated approaches combining atomic force microscopy, electron microscopy and biophysical techniques
    Ubbink, J
    Schär-Zammaretti, P
    MICRON, 2005, 36 (04) : 293 - 320
  • [24] Advanced atomic force microscopy techniques
    Glatzel, Thilo
    Hoelscher, Hendrik
    Schimmel, Thomas
    Baykara, Mehmet Z.
    Schwarz, Udo D.
    Garcia, Ricardo
    BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 2012, 3 : 893 - 894
  • [25] Single-cell elastography: Probing for disease with the atomic force microscope
    Costa, KD
    DISEASE MARKERS, 2003, 19 (2-3) : 139 - 154
  • [26] Monitoring of adipogenic differentiation at the single-cell level using atomic force microscopic analysis
    Kwon, Young-Nam
    Kim, Won Kon
    Lee, Sang-Hak
    Kim, Keewon
    Kim, Eun Young
    Ha, Tai Hwan
    Han, HyoukSoo
    Bae, Kwang-Hee
    SPECTROSCOPY-BIOMEDICAL APPLICATIONS, 2011, 26 (06): : 329 - 335
  • [27] Elemental Identification by Combining Atomic Force Microscopy and Kelvin Probe Force Microscopy
    Schulz, Fabian
    Ritala, Juha
    Krejci, Ondrej
    Seitsonen, Ari Paavo
    Foster, Adam S.
    Liljeroth, Peter
    ACS NANO, 2018, 12 (06) : 5274 - 5283
  • [28] Optical force microscopy: combining light with atomic force microscopy for nanomaterial identification
    Jahan, Nusrat
    Wang, Hanwei
    Zhao, Shensheng
    Dutta, Arkajit
    Huang, Hsuan-Kai
    Zhao, Yang
    Chen, Yun-Sheng
    NANOPHOTONICS, 2019, 8 (10) : 1659 - 1671
  • [29] Quantifying the Effect of Covalently Immobilized Enzymes on Biofilm Formation by Atomic Force Microscopy-Based Single-Cell Force Spectroscopy
    Friedrichs, Jens
    Zieris, Andrea
    Prokoph, Silvana
    Werner, Carsten
    MACROMOLECULAR RAPID COMMUNICATIONS, 2012, 33 (17) : 1453 - 1458
  • [30] Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM): Complementary techniques for high resolution surface investigations
    Russell, P
    Batchelor, D
    Thornton, J
    Surface Modification Technologies XV, 2002, : 109 - 118