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Invasive pneumococcal surveillance to assess the potential benefits of extended spectrum conjugate vaccines (PCV15/PCV20) in older adults
被引:2
|作者:
Humphreys, Hilary
[1
]
Corcoran, Mary
[1
,2
]
Mereckiene, Jolita
[4
]
Cunney, Robert
[1
,2
,3
]
Cotter, Suzanne
[4
]
机构:
[1] Ireland Univ Med & Hlth Sci, Royal Coll Surg, Dept Clin Microbiol, Dublin, Ireland
[2] Childrens Hlth Ireland Temple St, Irish Meningitis & Sepsis Reference Lab, Dublin, Ireland
[3] Childrens Hlth Ireland Temple St, Dept Microbiol, Dublin, Ireland
[4] Hlth Protect Surveillance Ctr, Hlth Serv Execut, Dublin, Ireland
来源:
基金:
欧盟地平线“2020”;
关键词:
Conjugated vaccines;
elderly;
invasive pneumococcal disease;
PCV13;
PCV15;
PCV20;
PPV23;
serotypes;
strategy;
STREPTOCOCCUS-PNEUMONIAE;
DISEASE;
IMMUNOGENICITY;
IRELAND;
SAFETY;
D O I:
10.1017/S0950268823000110
中图分类号:
R1 [预防医学、卫生学];
学科分类号:
1004 ;
120402 ;
摘要:
The introduction of pneumococcal conjugate vaccines (PCV) into the childhood vaccination programme has reduced invasive pneumococcal disease (IPD). Although anticipated from data elsewhere, surveillance in Ireland has confirmed reductions in IPD amongst those > 65 years of age due to a decline of PCV serotypes in this age group. Currently, direct protection against IPD in the elderly is focused on immunisation with the 23-valent pneumococcal polysaccharide vaccine (PPV23). However, immunity may not be as effective as with PCV and, furthermore, PPV23 uptake is poor in Ireland. Hence, consideration should be given to providing a PCV to this age group.
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页数:4
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