Risks of Proton Pump Inhibitors in Patients with Cirrhosis: Please Peruse the Indications

被引:1
|
作者
Low, En Xian Sarah [1 ]
Wang, Yen-Po [1 ,3 ]
Lu, Ching-Liang [1 ,2 ,3 ]
机构
[1] Taipei Vet Gen Hosp, Endoscopy Ctr Diag & Treatment, Dept Med, Taipei, Taiwan
[2] Natl Yang Ming Chiao Tung Univ, Inst Brain Sci, Taipei, Taiwan
[3] Natl Yang Ming Chiao Tung Univ, Fac Med, Taipei, Taiwan
关键词
Cirrhosis; Proton pump inhibitors; Hepatocellular carcinoma; Hepatic decompensation; Spontaneous bacterial peritonitis;
D O I
10.1007/s10620-023-08153-3
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The use of proton pump inhibitor (PPI) in cirrhotic patients can be associated with increased risks of long-term mortality, decompensation, hepatic encephalopathy, spontaneous bacterial peritonitis, and infection, but not with short-term mortality. Ensure clear indications at lowest effective dose of is mandatory for the use of PPI among cirrhotic patients.
引用
收藏
页码:7 / 9
页数:3
相关论文
共 50 条
  • [41] An educational intervention that effectively reduces the inappropriate administration of proton pump inhibitors in patients with cirrhosis
    Palomique, Juvelyn
    Ayoub, Walid
    Kuo, Alexander
    Noureddin, Mazen
    Sundaram, Vinay
    Brecht, Mary-Lynn
    Yang, Ju Dong
    JOURNAL OF HEPATOLOGY, 2021, 75 : S361 - S361
  • [42] PROTON PUMP INHIBITORS INCREASE THE RISK FOR HEPATIC ENCEPHALOPATHY IN CIRRHOSIS
    Dam, G.
    Vilstrup, H.
    Watson, H.
    Jepsen, P.
    JOURNAL OF HEPATOLOGY, 2015, 62 : S367 - S367
  • [43] Proton pump inhibitors in cirrhosis: Tradition or evidence based practice?
    Lodato, Francesca
    Azzaroli, Francesco
    Di Girolamo, Maria
    Feletti, Valentina
    Cecinato, Paolo
    Lisotti, Andrea
    Festi, Davide
    Roda, Enrico
    Mazzella, Giuseppe
    WORLD JOURNAL OF GASTROENTEROLOGY, 2008, 14 (19) : 2980 - 2985
  • [44] Proton pump inhibitors in cirrhosis:Tradition or evidence based practice?
    Francesca Lodato
    Francesco Azzaroli
    Maria Di Girolamo
    Valentina Feletti
    Paolo Cecinato
    Andrea Lisotti
    Davide Festi
    Enrico Roda
    Giuseppe Mazzella
    World Journal of Gastroenterology, 2008, (19) : 2980 - 2985
  • [45] Deleterious effect of proton pump inhibitors on the disease course of cirrhosis
    Janka, Tamas
    Tornai, Tamas
    Borbely, Brigitta
    Tornai, David
    Altorjay, Istvan
    Papp, Maria
    Vitalis, Zsuzsanna
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2020, 32 (02) : 257 - 264
  • [46] Deleterious effect of proton pump inhibitors on the disease course of cirrhosis
    Vitalis, Z.
    Janka, T.
    Tornai, T.
    Tornai, I.
    Tornai, D.
    Papp, M.
    JOURNAL OF HEPATOLOGY, 2018, 68 : S714 - S714
  • [47] The Indication, dosage and duration of proton pump inhibitors in liver cirrhosis
    De Roza, M.
    Chen, J. H.
    JOURNAL OF HEPATOLOGY, 2018, 68 : S747 - S747
  • [48] Proton pump inhibitors in pediatric patients
    Fan, Ellen
    Gavura, Scott
    Ruddock, Brent
    CANADIAN PHARMACISTS JOURNAL, 2006, 139 (05) : 53 - 55
  • [49] Proton Pump Inhibitors in cancer patients: How useful they are? A review of the most common indications for their use
    Numico, Gianmauro
    Fusco, Vittorio
    Franco, Pierfrancesco
    Rolla, Fausto
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2017, 111 : 144 - 151
  • [50] Proton pump inhibitors: balancing the benefits and potential fracture risks
    Richards, J. Brent
    Goltzman, David
    CANADIAN MEDICAL ASSOCIATION JOURNAL, 2008, 179 (04) : 306 - 307