Targeting mRNA translation in CLL

被引：0
|
作者：
Kueppers, Ralf [1 ]
机构：
[1] Univ Duisburg Essen, Duisburg, Germany
来源：
BLOOD | 2023年 / 141卷 / 26期
关键词：
EXPRESSION;
D O I：
10.1182/blood.2023020420
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this issue of Blood, Largeot et al(1) show that flavagline FL3-mediated inhibition of enhanced messenger RNA (mRNA) translation in chronic lymphocytic leukemia (CLL) cells has multiple effects, including blocking proliferation, rewiring MYC-driven metabolism, and controlling CLL growth in a murine model.
引用
收藏
页码：3129 / 3130
页数：2
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