An adaptive network model of the role of the microbiome-gut-brain axis in insomnia

被引：1

作者：

Banerjee, Sulagna ^{[1
]}

Chitty, Claudia ^{[2
]}

Lee, Quinn ^{[3
]}

Treur, Jan ^{[4
]}

机构：

[1] Woosong Univ, Artificial Intelligence, Daejeon, South Korea

[2] Univ Kent, Fac Sci Biol Sci Comp, Canterbury, England

[3] Univ Alabama, Math, Tuscaloosa, AL USA

[4] Vrije Univ Amsterdam, Social AI, Amsterdam, Netherlands

来源：

COGNITIVE SYSTEMS RESEARCH | 2023年 / 78卷

关键词：

Gut-Brain axis; Microbiome; Insomnia; Adaptive network model; Self; modelling network; SLEEP;

D O I：

10.1016/j.cogsys.2022.12.002

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

This paper presents an adaptive network model simulating the role of the gut microbiome for triggering biological mechanisms that alter the circadian cycle, mood and insomnia via the microbiome-gut-brain axis. Simulation graphs provide insight into how these immune and endocrine pathways interact with each other when the levels of the probiotics, Lactobacillus and Bifidobacteria, and pathogenic bacteria were altered. Varying these factors in simulations produced different outcomes for insomnia and sleep deprivation.

引用

页码：106 / 121

页数：16

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