Vitamin B12 emerges as key player during cellular reprogramming

被引：0
|
作者：
Vilchez-Acosta, Alba [1 ]
Desdin-Mico, Gabriela [1 ]
Ocampo, Alejandro [1 ,2 ]
机构：
[1] Univ Lausanne, Fac Biol & Med, Dept Biomed Sci, Lausanne, Vaud, Switzerland
[2] EPITERNA SA, Epalinges, Vaud, Switzerland
来源：
NATURE METABOLISM | 2023年 / 5卷 / 11期
基金：
瑞士国家科学基金会;
关键词：
D O I：
10.1038/s42255-023-00917-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
By analysing the effect of disrupting microbiota during in vivo reprogramming, Kovatcheva et al. demonstrated that vitamin B-12-dependent metabolism is a limiting factor for cellular reprogramming and plasticity, and propose its therapeutic supplementation for the improvement of tissue repair.
引用
收藏
页码：1844 / 1845
页数：2
相关论文
共 50 条
  • [41] RADIOASSAY FOR SERUM VITAMIN B12 WITH USE OF SALIVA AS VITAMIN B12 BINDER
    CARMEL, R
    COLTMAN, CA
    JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1969, 74 (06): : 967 - &
  • [42] Effect of chemical and microbial vitamin B12 analogues on production of vitamin B12
    Thirupathaiah, Yeruva
    Rani, Chiliveri Swarupa
    Reddy, Marrivada Sudhakara
    Rao, Linga Venkateswar
    WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2012, 28 (05): : 2267 - 2271
  • [43] Effect of chemical and microbial vitamin B12 analogues on production of vitamin B12
    Yeruva Thirupathaiah
    Chiliveri Swarupa Rani
    Marrivada Sudhakara Reddy
    Linga Venkateswar Rao
    World Journal of Microbiology and Biotechnology, 2012, 28 : 2267 - 2271
  • [44] Enhanced cellular uptake of polymers targeted with vitamin B12 and folate
    Russell-Jones, G
    McTavish, K
    McEwan, J
    JOURNAL OF CONTROLLED RELEASE, 2003, 91 (1-2) : 259 - 260
  • [45] Cellular uptake of vitamin B12 in patients with chronic renal failure
    Obeid, R
    Kuhlmann, M
    Kirsch, CM
    Herrmann, W
    NEPHRON CLINICAL PRACTICE, 2005, 99 (02): : C42 - C48
  • [46] VITAMIN B12 ABSORPTION STUDIES - COMPARISON OF 57CO VITAMIN B12 PLASMA LEVELS WITH AND WITHOUT PARENTERAL VITAMIN B12
    ARMSTRONG, BK
    WOODLIFF, HJ
    MEDICAL JOURNAL OF AUSTRALIA, 1969, 2 (14) : 692 - +
  • [47] Chemistry and cellular biochemistry of the vitamin B12 derivatives thiolatocobalamins.
    Suarez-Moreira, E
    Ziegler, CJ
    Jacobsen, DW
    Brasch, NE
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U1044 - U1044
  • [48] Two Distinct Thermodynamic Gradients for Cellular Metalation of Vitamin B12
    Young, Tessa R.
    Deery, Evelyne
    Foster, Andrew W.
    Martini, Maria Alessandra
    Osman, Deenah
    Warren, Martin J.
    Robinson, Nigel J.
    JACS AU, 2023, 3 (05): : 1472 - 1483
  • [49] The binding properties of the human receptor for the cellular uptake of vitamin B12
    Quadros, EV
    Nakayama, Y
    Sequeira, JM
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005, 327 (04) : 1006 - 1010
  • [50] Vitamin B12 and homocysteine
    Ray, JG
    Cole, DEC
    CANADIAN MEDICAL ASSOCIATION JOURNAL, 2005, 173 (11) : 1359 - 1360
12345