Midnolin-proteasome pathway for protein degradation

被引：2
|
作者：
Jin, Wei-Lin [1 ]
机构：
[1] Lanzhou Univ, Hosp 1, Clin Med Coll 1, Inst Canc Neurosci,Med Frontier Innovat Res Ctr, Lanzhou, Peoples R China
来源：
MEDCOMM | 2023年 / 4卷 / 06期
关键词：
GENES;
D O I：
10.1002/mco2.450
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Overexpression of immediate-early genes (IEGs) has been linked to was associated with cancer progression and prognosis. In a recent study, Gu et al. reported the midnolin-proteasome pathway, a novel ubiquitin-independent proteasomal degradation. 1 The study provided the mechanism of rapid degradation for nuclear proteins with high unsteadiness. Targeting the midnolin-proteasome pathway might be beneficial for cancer therapy.image
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页数：3
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