The nuclear pore complex as a platform for epigenetic regulation

被引：2
|
作者：
Brickner, Jason H. [1 ]
机构：
[1] Northwestern Univ, Dept Mol Biosci, Evanston, IL 60208 USA
来源：
JOURNAL OF CELL BIOLOGY | 2023年 / 222卷 / 09期
关键词：
D O I：
10.1083/jcb.202307078
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The nuclear pore complex (NPC) both mediates exchange of proteins and RNA between the nucleus and the cytoplasm and physically interacts with chromatin to regulate transcription. In this issue of JCB, Kumar et al. (2023. J. Cell Biol.) provide new insight into the molecular basis for NPC-mediated epigenetic silencing through loading of the replication processivity factor PCNA.
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页数：2
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