We study the problem of unbiased estimation of expectations with respect to (w.r.t.) pi a given, general probability measure on (R-d, B(R-d)) that is absolutely continuous with respect to a standard Gaussian measure. We focus on simulation associated to a particular class of diffusion processes, sometimes termed the Schrodinger-Follmer Sampler, which is a simulation technique that approximates the law of a particular diffusion bridge process {X-t}(t is an element of[0,1]) on R-d, d is an element of N-0. This latter process is constructed such that, starting at X-0 = 0, one has X-1 similar to pi. Typically, the drift of the diffusion is intractable and, even if it were not, exact sampling of the associated diffusion is not possible. As a result, [10,16] consider a stochastic Euler-Maruyama scheme that allows the development of biased estimators for expectations w.r.t. pi. We show that for this methodology to achieve a mean square error of O(epsilon(2)), for arbitrary epsilon > 0, the associated cost is O(epsilon(-5)). We then introduce an alternative approach that provides unbiased estimates of expectations w.r.t. pi, that is, it does not suffer from the time discretization bias or the bias related with the approximation of the drift function. We prove that to achieve a mean square error of O(epsilon(2)), the associated cost (which is random) is, with high probability, O(epsilon(-2)vertical bar log(epsilon)vertical bar(2+delta)), for any delta > 0. We implement our method on several examples including Bayesian inverse problems. (C) 2022 Elsevier Inc. All rights reserved.