Quantitative MYD88 L265P Analysis Represents a Powerful Tool for Assessing Disease Response and Evaluating Clinical Trial Performance in Waldenstrom's Macroglobulinemia

被引:0
|
作者
Tsakmaklis, Nickolas [1 ]
Hunter, Zachary R. [1 ]
Liu, Xia [1 ]
Kofides, Amanda [1 ]
Liu, Shirong [1 ]
Canning, Alexa G. [1 ]
Richardson, Kris [1 ]
Guerrera, Maria Luisa [1 ]
Patterson, Christopher J. [1 ]
Meid, Kirsten [1 ]
White, Timothy P. [1 ]
Little, Megan [1 ]
Stockman, Katherine [1 ]
Gustine, Joshua [1 ]
Flynn, Catherine A. [1 ]
Branagan, Andrew R. [2 ]
Sarosiek, Shayna R. [1 ]
Castillo, Jorge J. [1 ]
Treon, Steven P. [1 ]
机构
[1] Dana Farber Canc Inst, Bing Ctr Waldenstrom Macroglobulinemia, Boston, MA USA
[2] Massachusetts Gen Hosp Canc Ctr, Ctr Multiple Myeloma, Boston, MA USA
关键词
D O I
10.1182/blood-2023-190520
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Successful treatment of refractory cold hemagglutinemia in MYD88 L265P mutation-negative Waldenstrom's macroglobulinemia with bortezomib
    Izumi, Mayuko
    Tsunemine, Hiroko
    Suzuki, Yasuhiro
    Tomita, Akihiro
    Kusumoto, Toshiko
    Kodaka, Taiichi
    Itoh, Kiminari
    Takahashi, Takayuki
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2015, 102 (02) : 238 - 243
  • [22] MicroRNA-21 and-155 Are Induced by a Widely Expressed Mutation in MyD88 (L265P) in Waldenstrom's Macroglobulinemia
    Cao, Yang
    Hunter, Zachary
    Zhou, Yangsheng
    Liu, Xia
    Yang, Guang
    Xu, Lian
    Patterson, Christopher
    Treon, Steven P.
    BLOOD, 2011, 118 (21) : 1692 - 1692
  • [23] Detection Of MYD88 L265P In Peripheral Blood Of Patients With Waldenstrom's Macroglobulinemia and IgM Monoclonal Gammopathy Of Undetermined Significance
    Xu, Lian
    Hunter, Zachary
    Yang, Guang
    Zhou, Yangsheng
    Liu, Xia
    Cao, Yang
    Manning, Robert
    Patterson, Christopher
    Tripsas, Christina K.
    Kanan, Sandra
    Chen, Jiaji G.
    Lindeman, Neil I.
    Treon, Steven Peter
    BLOOD, 2013, 122 (21)
  • [24] MYD88 L265P is a marker highly characteristic of, but not restricted to, Waldenström’s macroglobulinemia
    C Jiménez
    E Sebastián
    M C Chillón
    P Giraldo
    J Mariano Hernández
    F Escalante
    T J González-López
    C Aguilera
    A G de Coca
    I Murillo
    M Alcoceba
    A Balanzategui
    M E Sarasquete
    R Corral
    L A Marín
    B Paiva
    E M Ocio
    N C Gutiérrez
    M González
    J F San Miguel
    R García-Sanz
    Leukemia, 2013, 27 : 1722 - 1728
  • [25] A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenstrom macroglobulinemia
    Yang, Guang
    Zhou, Yangsheng
    Liu, Xia
    Xu, Lian
    Cao, Yang
    Manning, Robert J.
    Patterson, Christopher J.
    Buhrlage, Sara J.
    Gray, Nathanael
    Tai, Yu-Tzu
    Anderson, Kenneth C.
    Hunter, Zachary R.
    Treon, Steven P.
    BLOOD, 2013, 122 (07) : 1222 - 1232
  • [26] Prognostic Impact of MYD88 L265P Mutation By Droplet Digital PCR in IgM MGUS and Smoldering Waldenstrom Macroglobulinemia
    Moreno, David F.
    Paz, Sara
    Mena, Mari-Pau
    Lopez-Guerra, Monica
    Oliver-Caldes, Aina
    Battram, Anthony M.
    Gerardo Rodriguez-Lobato, Luis
    Tovar, Natalia
    Teresa Cibeira, M.
    Jimenez-Segura, Raquel
    Blade Creixenti, Joan
    Rosinol, Laura
    Colomer, Dolors
    Fernandez de Larrea, Carlos
    BLOOD, 2021, 138
  • [27] Pleural fluid MYD88 L265P mutation supporting diagnosis and decision to treat extramedullary Waldenstrom's macroglobulinemia: a case report
    Barnes, Martin
    Sharma, Pritha
    Kumar, Vikas
    Kaell, Alan
    LiPera, William
    JOURNAL OF MEDICAL CASE REPORTS, 2020, 14 (01)
  • [28] Pleural fluid MYD88 L265P mutation supporting diagnosis and decision to treat extramedullary Waldenstrom’s macroglobulinemia: a case report
    Martin Barnes
    Pritha Sharma
    Vikas Kumar
    Alan Kaell
    William LiPera
    Journal of Medical Case Reports, 14
  • [29] Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenstrom's Macroglobulinemia: Correlation with MYD88 L265P Somatic Mutation Status, Clinical Features, and Outcome
    Petrikkos, Loizos
    Kyrtsonis, Marie-Christine
    Roumelioti, Maria
    Georgiou, George
    Efthymiou, Anna
    Tzenou, Tatiana
    Panayiotidis, Panayiotis
    BIOMED RESEARCH INTERNATIONAL, 2014, 2014
  • [30] First Latin America report on the diagnostic utility of the study of the MYD88 L265P gene mutation in patients with Waldenstrom Macroglobulinemia
    Giuliani, F.
    Pavlovsky, M. A.
    Giere, I.
    Fernandez, I.
    Sackmann, F.
    Pavlovsky, A.
    Remaggi, G.
    Castillo, J. J.
    ANNALS OF HEMATOLOGY, 2022, 101 (10) : 2365 - 2367