Molecularly imprinted and cladded polymers for constructing a portable plasmonic immunoassay for peptides in biofluids

被引：5
|
作者：
Guo, Zhanchen [1 ]
Zhang, Qi [1 ]
Xing, Rongrong [1 ]
Liu, Zhen [1 ]
机构：
[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Analyt Chem Life Sci, Nanjing 210023, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 21期
基金：
中国国家自然科学基金;
关键词：
C-PEPTIDE; TRACE GLYCOPROTEINS; COMPLEX; RECOGNITION; ASSAY;
D O I：
10.1039/d2cc06550a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Using two molecularly imprinted and cladded polymers (cMIPs), an inexpensive, fast and portable plasmonic immuno-sandwich assay (PISA) was rationally developed for high-specificity and ultra-sensitive detection of C-peptide in urine. The dual cMIPs-based PISA allowed healthy individuals to be distinguished from diabetes patients and exhibited several significant merits over existing immunoassays, holding great promise in clinical diagnosis.
引用
收藏
页码：3075 / 3078
页数：4
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