Solubility and thermodynamic analysis of 1-(4-tert-butyl-2,6-dimethylphenyl)ethenone in different pure and binary solvents

In this work, the solubility of 1-(4-tert-butyl-2,6-dimethylphenyl)ethenone was measured and correlated by isothermal saturation method in eight pure solvents (isopropyl alcohol, n-octanol, ethyl acetate, acetonitrile, ethanol, acetone, cyclohexane, methanol) and two binary solvents (isopropyl alcohol + ethyl acetate, ethanol + acetonitrile) at temperatures ranging from 273.15 K to 308.15 K. The results show that the solubility of 1-(4-tertbutyl-2,6-dimethylphenyl)ethenone in the selected solvent is positively correlated with temperature. The experimental solubility data were correlated by six thermodynamic models, including Van't Hoff equation, modified Apelblat equation, NRTL model, Wilson model, Jouyban - Acree model and Sun model. The values of RAD and RMSD showed that these models fit the solubility data well. Besides, Hansen solubility parameter was used to reveal the solubility behavior of 1-(4-tert-butyl-2,6-dimethylphenyl)ethenone. Finally, the thermodynamic propertie Delta solHO, Delta solSO, Delta solGO, %xi H and %xi TS were calculated by van't Hoff equation. The results showed Delta solHO, Delta solGO, Delta solSO, are all positive values, indicating that the dissolution process in selected solvents was entropy-driven and endothermic.