Development and characterisation of KRASmulti inhibitors for the treatment of KRAS mutant pancreatic ductal adenocarcinoma

被引：0
|
作者：
Tedeschi, Antonio
Schaaf, Otmar
Gmachl, Michael
Herdeis, Lorenz
Rocchetti, Francesca
Popow, Johannes
Schischlik, Fiorella
Gerlach, Daniel
Lipp, Jesse
Broker, Joachim
Mantoulidis, Andreas
Smethurst, Chris
Kessler, Dirk
Boettcher, Jark
Wunberg, Tobias
Santoro, Valeria
Waterson, Alex
Phan, Jason
Little, Andrew
Abbott, Jason
Sun, Qi
Fesik, Stephen
Mcconnell, Darryl
Pearson, Mark A.
Kraut, Norbert
Rudolph, Dorothea
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 02期
关键词：
D O I：
10.1158/1538-7445.PANCA2023-B103
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
B103
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Transcriptomic characterisation of the diabetogenic pancreatic ductal adenocarcinoma phenotype
    Stott, Martyn
    Hasoon, Megan
    Oldfield, Lucy
    Soul, Jamie
    Halloran, Christopher
    Costello, Eithne
    BRITISH JOURNAL OF SURGERY, 2024, 111
  • [42] Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
    Tang, Shuai
    Duan, Yichen
    Yuan, Tao
    Hu, Yutinh
    Yuan, Liang
    Shen, Ning
    Fu, Yixian
    Pu, Congying
    Wang, Xiaomin
    Xu, Jun
    Lan, Xiaojing
    Zheng, Ying
    Zhou, Yu
    Zhu, Hong
    Ding, Jian
    Geng, Meiyu
    Huang, Min
    PHARMACOLOGICAL RESEARCH, 2023, 197
  • [43] Progression of KRAS mutant pancreatic adenocarcinoma during vemurafenib treatment in a patient with metastatic melanoma
    Grey, A.
    Cooper, A.
    McNeil, C.
    O'Toole, S.
    Thompson, J.
    Grimison, P.
    INTERNAL MEDICINE JOURNAL, 2014, 44 (06) : 597 - 600
  • [44] Differential Effects of Dietary Macronutrients on the Development of Oncogenic KRAS-Mediated Pancreatic Ductal Adenocarcinoma
    Zhu, Liang
    Ji, Juntao
    Ma, Jianjia
    Wang, Dan
    Liu, Muyun
    Du, James Xianxing
    Chen, Rong
    Hou, Wei
    Abbruzzese, James L.
    Logsdon, Craig D.
    Yang, Vincent W.
    Luo, Yongde
    Lu, Weiqin
    CANCERS, 2022, 14 (11)
  • [45] Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras
    Asahina, Kinji
    Balog, Steven
    Hwang, Edward
    Moon, Eugene
    Wan, Emily
    Skrypek, Kaitlin
    Chen, Yibu
    Fernandez, Jay
    Romo, Janet
    Yang, Qihong
    Lai, Keane
    French, Samuel W.
    Tsukamoto, Hidekazu
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 318 (02): : G265 - G276
  • [46] Inflammation and development of pancreatic ductal adenocarcinoma
    Shi, Juanjuan
    Xue, Jing
    CHINESE CLINICAL ONCOLOGY, 2019, 8 (02)
  • [47] Targeting KRAS for the potential treatment of pancreatic ductal adenocarcinoma: Recent advancements provide hope (Review)
    Zhang, Joshua
    Darman, Lily
    Hassan, Md Sazzad
    Von Holzen, Urs
    Awasthi, Niranjan
    ONCOLOGY REPORTS, 2023, 50 (05)
  • [48] Advances in Pancreatic Ductal Adenocarcinoma Treatment
    Anderson, Eric M.
    Thomassian, Shant
    Gong, Jun
    Hendifar, Andrew
    Osipov, Arsen
    CANCERS, 2021, 13 (21)
  • [49] Precision treatment of pancreatic ductal adenocarcinoma
    Wei, Hongyun
    Ren, He
    CANCER LETTERS, 2024, 585
  • [50] Neoadjuvant treatment of pancreatic ductal adenocarcinoma
    Katharina Kosma
    Sabine Thalhammer
    Thomas Gruenberger
    memo - Magazine of European Medical Oncology, 2022, 15 : 219 - 223
12345