Plastic additives comprise a plethora of substances that serve numerous purposes in the plastic industry. These can be used to assist the molding of plastics and can contribute to providing optimal performance to the material when molded and used, or, simply, to reduce costs. However, these additives, and nonpolymerized monomers, far more hazardous than their poly-counterparts, may be released throughout the entire life cycle of plastics, posing risks to the environment and, ultimately, human health. Hence, many studies have delved into the mechanistic uptake/release of these compounds. Herein, we briefly overview the current knowledge on the underlying processes affecting these mechanisms. We also outline the potential ecological consequences of these hazardous substances and explore some of the prevailing analytical methodologies used for their determination in both environment and laboratory studies. Furthermore, we highlight the key limitations of the currently available literature and present a prospective outlook for future research.(c) 2022 The Authors. Published by Elsevier B.V.This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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Univ Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Estevez-Danta, Andrea
Ayala-Cabrera, Juan F.
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Univ Basque Country UPV EHU, Dept Analyt Chem, Leioa, Spain
Univ Basque Country PiE UPV EHU, Res Ctr Expt Marine Biol & Biotechnol, Plentzia, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Ayala-Cabrera, Juan F.
Lopez-Vazquez, Javier
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Univ Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Lopez-Vazquez, Javier
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Musatadi, Mikel
Montes, Rosa
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Univ Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Montes, Rosa
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Etxebarria, Nestor
Quintana, Jose Benito
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Univ Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Quintana, Jose Benito
Olivares, Maitane
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Univ Basque Country UPV EHU, Dept Analyt Chem, Leioa, Spain
Univ Basque Country PiE UPV EHU, Res Ctr Expt Marine Biol & Biotechnol, Plentzia, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Olivares, Maitane
Prieto, Ailette
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Univ Basque Country UPV EHU, Dept Analyt Chem, Leioa, Spain
Univ Basque Country PiE UPV EHU, Res Ctr Expt Marine Biol & Biotechnol, Plentzia, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Prieto, Ailette
Rodil, Rosario
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Univ Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Rodil, Rosario
Miro, Manuel
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Univ Balear Isl UIB, Dept Chem, FI TRACE Grp, Palma De Mallorca, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
Miro, Manuel
Zuloaga, Olatz
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Univ Basque Country UPV EHU, Dept Analyt Chem, Leioa, Spain
Univ Basque Country PiE UPV EHU, Res Ctr Expt Marine Biol & Biotechnol, Plentzia, SpainUniv Santiago De Compostela USC, Inst Res Chem & Biol Anal IAQBUS, Dept Analyt Chem Nutr & Food Sci, Santiago De Compostela, Spain
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Univ Buenos Aires, Fac Sci, Dept Biol Chem, Lab Biosensors & Bioanal LABB, RA-1428 Buenos Aires, Argentina
Univ Buenos Aires, Fac Sci, IQUIBICEN, RA-1428 Buenos Aires, Argentina
Consejo Nacl Invest Cient & Tecn, RA-1428 Buenos Aires, Argentina
Natl Technol Univ, Fac Reg Gen Pacheco, Basic Sci Dept, Buenos Aires, ArgentinaUniv Buenos Aires, Fac Sci, Dept Biol Chem, Lab Biosensors & Bioanal LABB, RA-1428 Buenos Aires, Argentina
Mosquera-Ortega, Monica
de Sousa, Lucas Rodrigues
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Univ Buenos Aires, Fac Sci, Dept Biol Chem, Lab Biosensors & Bioanal LABB, RA-1428 Buenos Aires, Argentina
Univ Buenos Aires, Fac Sci, IQUIBICEN, RA-1428 Buenos Aires, Argentina
Consejo Nacl Invest Cient & Tecn, RA-1428 Buenos Aires, Argentina
Univ Fed Goias, Chem Inst, Campus Samambaia, Goiania, BrazilUniv Buenos Aires, Fac Sci, Dept Biol Chem, Lab Biosensors & Bioanal LABB, RA-1428 Buenos Aires, Argentina
de Sousa, Lucas Rodrigues
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Susmel, Sabina
Corton, Eduardo
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Univ Buenos Aires, Fac Sci, Dept Biol Chem, Lab Biosensors & Bioanal LABB, RA-1428 Buenos Aires, Argentina
Univ Buenos Aires, Fac Sci, IQUIBICEN, RA-1428 Buenos Aires, Argentina
Consejo Nacl Invest Cient & Tecn, RA-1428 Buenos Aires, Argentina
Indian Inst Technol Guwahati, Dept Biosci & Bioengn, Gauhati, Assam, IndiaUniv Buenos Aires, Fac Sci, Dept Biol Chem, Lab Biosensors & Bioanal LABB, RA-1428 Buenos Aires, Argentina
Corton, Eduardo
Figueredo, Federico
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Univ Buenos Aires, Fac Sci, Dept Biol Chem, Lab Biosensors & Bioanal LABB, RA-1428 Buenos Aires, Argentina
Univ Buenos Aires, Fac Sci, IQUIBICEN, RA-1428 Buenos Aires, Argentina
Consejo Nacl Invest Cient & Tecn, RA-1428 Buenos Aires, ArgentinaUniv Buenos Aires, Fac Sci, Dept Biol Chem, Lab Biosensors & Bioanal LABB, RA-1428 Buenos Aires, Argentina
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Kumamoto Univ, Grad Sch Sci & Technol, Chuo Ku, 2-39-1 Kurokami, Kumamoto 8608555, JapanKumamoto Univ, Grad Sch Sci & Technol, Chuo Ku, 2-39-1 Kurokami, Kumamoto 8608555, Japan
Tun, Thant Zin
Kunisue, Tatsuya
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Ehime Univ, Ctr Marine Environm Studies CMES, 2-5 Bunkyo Cho, Matsuyama, Ehime 7908577, JapanKumamoto Univ, Grad Sch Sci & Technol, Chuo Ku, 2-39-1 Kurokami, Kumamoto 8608555, Japan
Kunisue, Tatsuya
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Tanabe, Shinsuke
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Prudente, Maricar
Subramanian, Annamalai
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Bharathidasan Univ, Dept Environm Biotechnol, Sch Environm Sci, Tiruchirappalli 620024, IndiaKumamoto Univ, Grad Sch Sci & Technol, Chuo Ku, 2-39-1 Kurokami, Kumamoto 8608555, Japan
Subramanian, Annamalai
Sudaryanto, Agus
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Agcy Assessment & Applicat Technol BPPT, JL MH Thamrin 8, Jakarta, IndonesiaKumamoto Univ, Grad Sch Sci & Technol, Chuo Ku, 2-39-1 Kurokami, Kumamoto 8608555, Japan
Sudaryanto, Agus
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Pham Hung Viet
Nakata, Haruhiko
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Kumamoto Univ, Fac Adv Sci & Technol, Chuo Ku, 2-39-1 Kurokami, Kumamoto 860855, JapanKumamoto Univ, Grad Sch Sci & Technol, Chuo Ku, 2-39-1 Kurokami, Kumamoto 8608555, Japan
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Univ Las Palmas Gran Canaria, Inst Univ Estudios Ambient & Recursos Nat I UNAT, Las Palmas Gran Canaria 35017, SpainCampus Univ Penteada, CQM Ctr Quim Madeira, P-9020105 Funchal, Portugal
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Univ Las Palmas Gran Canaria, Inst Univ Estudios Ambient & Recursos Nat I UNAT, Las Palmas Gran Canaria 35017, SpainCampus Univ Penteada, CQM Ctr Quim Madeira, P-9020105 Funchal, Portugal
Guedes-Alonso, Rayco
Sosa-Ferrera, Zoraida
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Univ Las Palmas Gran Canaria, Inst Univ Estudios Ambient & Recursos Nat I UNAT, Las Palmas Gran Canaria 35017, SpainCampus Univ Penteada, CQM Ctr Quim Madeira, P-9020105 Funchal, Portugal