A Potential New Use for Tocilizumab: Refractory Checkpoint Inhibitor Hepatitis

被引:2
|
作者
Lyles, Laine [1 ]
Farmer, Reagan [2 ]
Abougergi, Marwan [3 ]
机构
[1] Univ South Carolina, Prisma Hlth, Columbia, SC 29208 USA
[2] Univ South Carolina, Sch Med Columbia, Columbia, SC USA
[3] Catalyst Med Consulting, Simpsonville, SC USA
关键词
autoimmune hepatitis; drug-induced autoimmune hepatitis; check point inhibitor; chemotherapy; renal cell carcinoma; hepatitis; drug induced liver injury; steroid refractory; tocilizumab; nivolumab; ipilimumab; CANCER;
D O I
10.14309/crj.0000000000001162
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Immune checkpoint inhibitors are becoming more commonly used for many forms of malignancy. With this class of medications being more heavily used, there has been an associated rise in medication-induced autoimmune hepatitis. This case involves a 35-year-old woman being treated with nivolumab/ipilimumab for renal cell carcinoma who developed a steroid-refractory autoimmune hepatitis.
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页数:3
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