Associations of concentrations of eight urinary phthalate metabolites with the frequency of use of common adult consumer and personal-care products

被引:3
|
作者
Jang, Eun A. [1 ]
Kim, Kyu Nam [1 ]
Bae, Sang Hyuk [2 ]
机构
[1] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Dept Plast & Reconstruct Surg, Seoul, South Korea
[2] Catholic Univ Korea, Coll Med, Dept Prevent Med, 222 Banpo Daero, Seoul 06591, South Korea
关键词
Phthalates; Cosmetics and air fresheners; Urine creatinine; Biological sample; PREGNANT-WOMEN; EXPOSURE; OBESITY; VARIABILITY; FRAGRANCE; HEALTH; ESTERS;
D O I
10.1038/s41598-024-55929-2
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This study analyzed the relationship between urine concentrations of phthalate metabolites (UCOM) and personal care products (PCPs) used in adults and examined the change in UCOM according to the usage frequency of PCPs based on raw data from the 3rd Korean National Environmental Health Survey conducted between 2015 and 2017. The relationship between PCP use frequency and UCOM was analyzed using multiple regression analysis, adjusting for baseline factors. The regression model consisted of a Crude Model with log-transformed UCOM before and after adjustment for urine creatinine concentrations. Model 1 was additionally adjusted for age, sex, and obesity, while Model 2 was additionally adjusted for smoking, alcohol consumption, pregnancy history, average monthly income of the household, and PCP exposure within the past 2 days. PCP usage frequency was significantly associated with the UCOM without adjustment for urine creatinine and correlated with demographic characteristics, urine creatinine concentration, and PCP exposure within the past 2 days. This study on exposure to urinary phthalates will play a crucial role in Korean public health by aligning with the fundamentals of research priorities and providing representative data on phthalate exposure for conducting population-level studies.
引用
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页数:12
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