The applications of 3D printing in wound healing: The external delivery of stem cells and antibiosis

被引：21

作者：

Yu, Qingtong ^{[1
]}

Wang, Qilong ^{[1
]}

Zhang, Linzhi ^{[1
]}

Deng, Wenwen ^{[1
]}

Cao, Xia ^{[1
]}

Wang, Zhe ^{[1
]}

Sun, Xuan ^{[1
]}

Yu, Jiangnan ^{[1
]}

Xu, Ximing ^{[1
]}

机构：

[1] Jiangsu Univ, Sch Pharm, Zhenjiang 212013, Peoples R China

来源：

ADVANCED DRUG DELIVERY REVIEWS | 2023年 / 197卷

基金：

美国国家科学基金会; 中国国家自然科学基金;

关键词：

Stem cells; 3D bioprinting; Skin regeneration; Antibiosis; Biofilm; Wound healing; SKIN REGENERATION; IN-VITRO; BIOFABRICATION STRATEGIES; ANTIMICROBIAL ACTIVITY; BACTERIAL CELLULOSE; CONTROLLED-RELEASE; DRUG-DELIVERY; PHAGE THERAPY; BONE-MARROW; HYDROGEL;

D O I：

10.1016/j.addr.2023.114823

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

As the global number of chronic wound patients rises, the financial burden and social pressure on patients increase daily. Stem cells have emerged as promising tissue engineering seed cells due to their enriched sources, multidirectional differentiation ability, and high proliferation rate. However, delivering them in vitro for the treatment of skin injury is still challenging. In addition, bacteria from the wound site and the environment can significantly impact wound healing. In the last decade, 3D bioprinting has dra-matically enriched cell delivery systems. The produced scaffolds by this technique can be precisely local-ized within cells and perform antibacterial actions. In this review, we summarized the 3D bioprinting-based external delivery of stem cells and their antibiosis to improve wound healing.CO 2023 Elsevier B.V. All rights reserved.

引用

页数：21

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