Indole-Fused Benzoxepine Synthesis via Visible-Light-Driven Aerobic Dehydrogenative [5+2] Annulation

被引：0

作者：

Dong, Kui ^{[1
]}

Zhao, Yi-Lin ^{[1
]}

Jin, Xiao-Ling ^{[1
]}

Liu, Qiang ^{[1
]}

机构：

[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

ORGANIC LETTERS | 2023年 / 25卷 / 46期

基金：

中国国家自然科学基金;

关键词：

ALKALOIDS;

D O I：

10.1021/acs.orglett.3c03310

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A photocatalyzed oxidative dehydrogenative annulation between 2-(1H-indol-2-yl)-phenols and alkenylphenols is presented. Various indole-fused benzoxepines can be obtained at room temperature using atom-efficient strategies. This method not only avoids the use of stoichiometric amounts of oxidants but also exhibits excellent atom economy by generating H2O as the only theoretical byproduct.

引用

页码：8258 / 8262

页数：5

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