Synthesis and Characterization of Benzimidazole Derivatives and Evaluation of Antimicrobial activity

被引：0
|
作者：
Vyas, Kamal Kant [1 ]
Rajpurohit, Sangeeta [2 ]
Vaishnav, Yudhishthir [1 ]
机构：
[1] JNVU Jodhpur, Dept Chem, Jodhpur 342001, Rajasthan, India
[2] Lachoo Mem Coll, Organ Iab, Jodhpur 342001, Rajasthan, India
来源：
ORIENTAL JOURNAL OF CHEMISTRY | 2023年 / 39卷 / 04期
关键词：
Benzimidazole; Antibacterial; Antifungal; ANTIBACTERIAL ACTIVITY;
D O I：
10.13005/ojc/390424
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A series of benzimidazole derivatives were synthesized for this investigation. NMR and IR spectrum analysis as well as carbon, hydrogen, and nitrogen studies were used to characterize these novel synthesized derivatives. Antibacterial and antifungal tests were conducted on all of the newly synthesized compounds. Ciprofloxacin and fluconazole were utilized as reference medications in antibacterial and antifungal research, respectively. The microbiological assay revealed that the compounds show promising antibacterial and antifungal activity.
引用
收藏
页码：996 / 1001
页数：6
相关论文
共 50 条
  • [31] Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives
    Parab, R. H.
    Dixit, B. C.
    Desai, D. J.
    ASIAN JOURNAL OF CHEMISTRY, 2011, 23 (06) : 2725 - 2728
  • [32] Synthesis, Characterization and Biological Activity of Benzimidazole-acrylonitrile Derivatives
    Parveen, Mehtab
    Azeem, Mohammad
    Aslam, Afroz
    Haris, Mohammad
    Khan, Amir
    Alam, Mahboob
    CURRENT ORGANIC SYNTHESIS, 2023, 20 (04) : 458 - 469
  • [33] SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF BENZIMIDAZOLE INCORPORATED PYRAZOLE DERIVATIVES
    Kumari, Maddineni Aruna
    Venkatarao, Chunduri
    Triloknadh, Settypalli
    HETEROCYCLIC LETTERS, 2020, 10 (02): : 231 - 243
  • [34] Synthesis, characterization and biological activity of some novel benzimidazole derivatives
    Jafar, Ahamed A.
    Vijayakumar, Kaliapillai N.
    Venkatraman, Bathey R.
    Venkatesh, Govindaraj
    ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY, 2009, 1 (04): : 306 - 309
  • [35] SYNTHESIS, CHARACTERIZATION AND DPPH SCAVENGING ACTIVITY OF SOME BENZIMIDAZOLE DERIVATIVES
    Odame, Felix
    Krause, Jason
    Hosten, Eric C.
    Betz, Richard
    Lobb, Kevin
    Tshentu, Zenixole R.
    Frost, Carminita L.
    BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA, 2018, 32 (02) : 271 - 284
  • [36] Synthesis, characterization and biological evaluation of some novel Benzimidazole derivatives
    Ahmadi, A.
    BULGARIAN CHEMICAL COMMUNICATIONS, 2014, 46 (02): : 245 - 252
  • [37] Synthesis, Characterization, and Biological Evaluation of Benzimidazole Derivatives as Potential Anxiolytics
    Nannapaneni, D. T.
    Atyam, Gupta V. S. S. S.
    Reddy, M., I
    Raidu, Sarva Ch
    JOURNAL OF YOUNG PHARMACISTS, 2010, 2 (03) : 273 - 279
  • [38] Antimicrobial Activity of a New Series of Benzimidazole Derivatives
    Ozkay, Yusuf
    Tunali, Yagmur
    Karaca, Hulya
    Isikdag, Ilhan
    ARCHIVES OF PHARMACAL RESEARCH, 2011, 34 (09) : 1427 - 1435
  • [39] Antimicrobial activity of a new series of benzimidazole derivatives
    Yusuf Özkay
    Yağmur Tunalı
    Hülya Karaca
    İlhan Işıkdağ
    Archives of Pharmacal Research, 2011, 34 : 1427 - 1435
  • [40] Synthesis and Evaluation of Antimicrobial Activity of Thiazolidinone Derivatives
    Veerasamy, Ravichandran
    Rajak, Harish
    Kumar, Krishnan Suresh
    Agrawal, Ram Kishore
    LETTERS IN DRUG DESIGN & DISCOVERY, 2011, 8 (01) : 82 - 86
12345