A B7-H4 targeting antibody-drug conjugate shows anti-tumor activity in PARPi and platinum resistant cancers with B7-H4 expression

被引:0
|
作者
Gitto, Sarah B.
Whicker, Margaret
Davies, Gareth
Kumar, Sushil
Kinneer, Krista
Lewis, Arthur
Mamidi, Srinivas
Medvedev, Sergey
Anderton, Judith
Tang, Jessica
Ferman, Benjamin
Coats, Steve
Wilkinson, Robert W.
Brown, Eric J.
Powell, Daniel J.
Simpkins, Fiona
机构
关键词
D O I
10.1158/1538-7445.AM2023-1133
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1133
引用
收藏
页数:3
相关论文
共 50 条
  • [21] B7-H4, a promising target for immunotherapy
    Wang, Jia-Yu
    Wang, Wei-Peng
    CELLULAR IMMUNOLOGY, 2020, 347
  • [22] EXPRESSION OF B7-H4 ON TUBULE CELLS IN DIABETIC NEPHROPATHY
    Cao, Q.
    Wang, Y.
    Zheng, D.
    Sun, Y.
    Lee, V.
    Zheng, G.
    Harris, D.
    NEPHROLOGY, 2008, 13 : A138 - A138
  • [23] Expression of costimulatory molecules B7-H4 in PBC patients
    Zhao, Chen
    Zhao, Yang
    Li, Yong-zhe
    Hu, Chao-jun
    Liu, Ding-hua
    ADVANCES IN APPLIED SCIENCES AND MANUFACTURING, PTS 1 AND 2, 2014, 850-851 : 1216 - +
  • [24] B7-H4 Expression in Precancerous Lesions of the Uterine Cervix
    Zhang, Qianqian
    Zong, Liju
    Zhang, Hui
    Xie, Wei
    Yang, Fan
    Sun, Wenwen
    Cui, Baoxia
    Zhang, Youzhong
    BIOMED RESEARCH INTERNATIONAL, 2021, 2021
  • [25] Targeting the Negative Immune Regulatory Molecule B7-H4 on Both Tumor and Normal Tissue With Anti-B7-H4 CAR T Cells
    Smith, Jenessa B.
    Lanitis, Evripidis
    Dangaj, Denarda
    Poussin, Mathilde
    McLane, Michael
    Scholler, Nathalie
    Powell, Daniel J.
    MOLECULAR THERAPY, 2015, 23 : S206 - S206
  • [26] Upregulation of B7-H4 promotes tumor progression of intrahepatic cholangiocarcinoma
    Xie, Nan
    Cai, Jia-Bin
    Zhang, Lu
    Zhang, Peng-Fei
    Shen, Ying-Hao
    Yang, Xuan
    Lu, Jia-Cheng
    Gao, Dong-Mei
    Kang, Qiang
    Liu, Li-Xin
    Zhang, Chi
    Huang, Xiao-Yong
    Zou, Hao
    Zhang, Xin-Yu
    Song, Zheng-Ji
    Sun, Hai-Xiang
    Fu, Bi-Mang
    Ke, Ai-Wu
    Shi, Guo-Ming
    CELL DEATH & DISEASE, 2017, 8
  • [27] Downregulation of B7-H4 suppresses tumor progression of hepatocellular carcinoma
    Lijie Dong
    Lulu Xie
    Minjing Li
    Hanhan Dai
    Xia Wang
    Peiyuan Wang
    Qiang Zhang
    Wei Liu
    Xuemei Hu
    Mingdong Zhao
    Scientific Reports, 9
  • [28] The expression of B7-H3 and B7-H4 in human gallbladder carcinoma and their clinical implications
    Liu, C. -L.
    Zang, X. -X.
    Huang, H.
    Zhang, H.
    Wang, C.
    Kong, Y. -L.
    Zhang, H. -Y.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2016, 20 (21) : 4466 - 4473
  • [29] Upregulation of B7-H4 promotes tumor progression of intrahepatic cholangiocarcinoma
    Nan Xie
    Jia-Bin Cai
    Lu Zhang
    Peng-Fei Zhang
    Ying-Hao Shen
    Xuan Yang
    Jia-Cheng Lu
    Dong-Mei Gao
    Qiang Kang
    Li-Xin Liu
    Chi Zhang
    Xiao-Yong Huang
    Hao Zou
    Xin-Yu Zhang
    Zheng-Ji Song
    Hai-Xiang Sun
    Bi-Mang Fu
    Ai-Wu Ke
    Guo-Ming Shi
    Cell Death & Disease, 8
  • [30] B7-H4 expression in Brenner tumours, a descriptive and comparative study
    Yee, Eric U.
    Zaino, Richard J.
    Torkko, Kathleen C.
    Shroyer, Kenneth R.
    HISTOPATHOLOGY, 2010, 56 (05) : 652 - 654