Efficacy of gelfoam middle ear packing in type-1 tympanoplasty: systematic review and meta-analysis

被引:2
|
作者
Albazee, Ebraheem [1 ]
Abu-Zaid, Ahmed [2 ,3 ]
Alshammari, Bader [1 ]
Salamah, Marzouqi [4 ]
Alolaywi, Ahmed Naif [5 ]
Almobarak, Abdulaziz A. [6 ]
Hagr, Abdulrahman [4 ]
机构
[1] Kuwait Inst Med Specializat KIMS, Kuwait, Kuwait
[2] Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia
[3] Univ Tennessee, Coll Grad Hlth Sci, Hlth Sci Ctr, Memphis, TN 38163 USA
[4] King Saud Univ, King Saud Univ Med City KSUMC, King Abdullah Ear Specialist Ctr KAESC, Coll Med, Riyadh, Saudi Arabia
[5] Aljouf Univ, Dept Otolaryngol, Aljouf, Saudi Arabia
[6] King Faisal Specialist Hosp & Res Ctr, Dept Otolaryngol Head & Neck, Riyadh, Saudi Arabia
关键词
Tympanoplasty; Gelfoam; Graft uptake; Hearing; Meta-analysis; ABSORBABLE GELATIN SPONGE; HYALURONIC-ACID; IN-VITRO; AGENTS;
D O I
10.1007/s00405-023-07975-1
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
PurposeTo conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) that evaluated the surgical outcomes of type-1 tympanoplasty with and without gelfoam middle ear packing.MethodsPubMed, CENTRAL, Scopus, Web of Science, and Google Scholar databases were screened from inception until October 2022. The included RCTs were evaluated for risk of bias, and the quality of each outcome was assessed according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system.ResultsNine RCTs with 773 participants (gelfoam = 381 and non-gelfoam = 392) were analyzed. The overall study quality varied: low risk (n = 4 RCTs), some concerns (n = 3 RCTs), and high risk (n = 2 RCTs). There were no significant differences between both arms regarding the graft uptake rate (moderate certainty), hearing improvement rate (moderate certainty), type of impedance audiometry (moderate certainty), and ear discharge (low certainty). The mean change in air-bone gap was significantly higher in the non-gelfoam arm compared with the gelfoam arm (low certainty). However, the non-gelfoam group had superior hearing improvement in only the early postoperative period (i.e., one month); however, after two, three, and six months, there were no significant differences between both arms. The rate of ear fullness was significantly higher in the gelfoam arm compared with the non-gelfoam arm (moderate certainty).ConclusionAmong patients undergoing type-1 tympanoplasty, the surgical outcomes did not significantly differ between both arms. The practice of middle ear packing with gelfoam needs to be standardized.
引用
收藏
页码:3503 / 3514
页数:12
相关论文
共 50 条
  • [21] Parental Smoking and the Risk of Middle Ear Disease in Children A Systematic Review and Meta-analysis
    Jones, Laura L.
    Hassanien, Amal
    Cook, Derek G.
    Britton, John
    Leonardi-Bee, Jo
    ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 2012, 166 (01): : 18 - 27
  • [22] Endoscopic-Guided Resection of Middle Ear Cholesteatoma: A Systematic Review and Meta-Analysis
    Giffoni, Rodolfo Baptista
    dos Santos, Gabriele
    Aguiar, Ricardo Santos
    Lins, Lucas Costa
    Cruz, Marcelo Leandro Santana
    Lima, Adriano Damasceno
    OTOLOGY & NEUROTOLOGY, 2025, 46 (04) : 418 - 424
  • [23] Middle ear congenital cholesteatoma: systematic review, meta-analysis and insights on its pathogenesis
    Nelson Gilberto
    Sara Custódio
    Tiago Colaço
    Ricardo Santos
    Pedro Sousa
    Pedro Escada
    European Archives of Oto-Rhino-Laryngology, 2020, 277 : 987 - 998
  • [24] Middle ear congenital cholesteatoma: systematic review, meta-analysis and insights on its pathogenesis
    Gilberto, Nelson
    Custodio, Sara
    Colaco, Tiago
    Santos, Ricardo
    Sousa, Pedro
    Escada, Pedro
    EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2020, 277 (04) : 987 - 998
  • [25] Comparing Myringoplasty to Type I Tympanoplasty in Tympanic Membrane Repair: A Systematic Review and Meta-Analysis
    Jungbauer Jr, Walter Nicholas
    Jeong, Seth
    Nguyen, Shaun A.
    Lambert, Paul R.
    OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2023, 168 (05) : 922 - 934
  • [26] Efficacy and Safety of Technology in Type 1 Diabetes: A Systematic Review and Network Meta-analysis
    Pease, Anthony J.
    Lo, Clement
    Earnest, Arul
    Kiriakova, Velislava
    Liew, Danny
    Zoungas, Sophia
    DIABETES, 2019, 68
  • [27] Is Cartilage Thickness Important in Cartilage Tympanoplasty? A Systematic Review and Meta-analysis
    Hamed Emami
    Reza Erfanian
    Sina Berijani
    Pouya Alizadeh
    Behrooz Amirzargar
    Indian Journal of Otolaryngology and Head & Neck Surgery, 2022, 74 : 456 - 462
  • [28] Efficacy and safety of bloodletting on ear apex for primary hypertension: A systematic review and meta-analysis
    Kwon, Chan-Young
    Lee, Boram
    Lee, Ju Ah
    EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE, 2018, 23 : 90 - 100
  • [29] Is Cartilage Thickness Important in Cartilage Tympanoplasty? A Systematic Review and Meta-analysis
    Emami, Hamed
    Erfanian, Reza
    Berijani, Sina
    Alizadeh, Pouya
    Amirzargar, Behrooz
    INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY, 2022, 74 (04) : 456 - 462
  • [30] Endoscopic versus microscopic surgery for treatment of middle ear cholesteatoma: A systematic review and meta-analysis
    Li, Bo
    Zhou, Lingyun
    Wang, Miaowei
    Wang, Yanwen
    Zou, Jian
    AMERICAN JOURNAL OF OTOLARYNGOLOGY, 2021, 42 (02)