Culture of care is critical in various contexts, particularly in health care organizations, because it fosters an environment where individuals feel respected, valued, and supported. This culture should embody well-being, teamwork, and trust. In health care organizations, creating a culture of care results in better patient experiences and clinical outcomes, and decreased burnout among staff. It is also fundamental for ethical conduct and patient-centeredness. Overall, it underpins the essence of compassion and kindness, which forms the bedrock of the health care industry. However, creating a culture of compassion, although essential, can be challenging. It is the cornerstone of success in health care. Developing this culture starts with a comprehensive understanding of core principles, including patient -centered care, leadership, physical and psychological wellbeing, safety, communication, inclusivity, and professional growth. The culture of care influences various outcomes for patients, families, nurses, and other health care employees. To foster this culture, organizations need to understand the various dynamics and scope from both patient and employee perspectives. Importantly, this responsibility falls upon organizational leadership, which must support, create, communicate, and model a culture of compassionate care. Providing compassionate care is mandatory and not a choice. With new changes in the dynamics of health care delivery, finances, and the emerging workforce, having a strong culture of care is more crucial than ever. Therefore, the commitment to compassionate care should extend beyond mere aspirations; it must become an intentional and integral part of organizational practices.