The role of the molecular autopsy in sudden cardiac death in young individuals

被引：3
|
作者：
Isbister, Julia C. [1 ,2 ]
Semsarian, Christopher [1 ,2 ,3 ]
机构：
[1] Univ Sydney, Fac Med & Heath, Sydney, NSW, Australia
[2] Royal Prince Alfred Hosp, Dept Cardiol, Sydney, NSW, Australia
[3] Univ Sydney, Centenary Inst, Agnes Ginges Ctr Mol Cardiol, Sydney, NSW, Australia
来源：
NATURE REVIEWS CARDIOLOGY | 2024年 / 21卷 / 4期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1038/s41569-024-00989-0
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A molecular autopsy is undertaken in cases of sudden cardiac death with no definitive cause found after conventional autopsy, with the aim of identifying a pathological genetic variant that could account for the death. Greater awareness of malignant arrhythmias in the absence of structural changes in inherited cardiomyopathies has increased the applicability of molecular autopsies, and resulted in improved care of families but new challenges for clinicians.
引用
收藏
页码：215 / 216
页数：2
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