Visualization of Intermetastatic Heterogeneity in Mixed Neuroendocrine Carcinoma-Acinar Adenocarcinoma of the Prostate by 68Ga-PSMA, 68Ga-FAPI, and 18F-FDG PET/CT

被引：4

作者：

Cai, Jiayu ^{[1
,2
]}

Xu, Weizhi ^{[1
,2
]}

Meng, Tinghua ^{[1
,2
]}

Pang, YiZhen ^{[1
,2
]}

Chen, Haojun ^{[1
,2
,3
]}

机构：

[1] Xiamen Univ, Affiliated Hosp 1, Xiamen Canc Ctr, Sch Med,Dept Nucl Med, Xiamen, Peoples R China

[2] Xiamen Univ, Affiliated Hosp 1, Minnan PET Ctr, Xiamen Canc Ctr,Sch Med, Xiamen, Peoples R China

[3] 55 Zhenhai Rd, Xiamen 361003, Peoples R China

来源：

CLINICAL NUCLEAR MEDICINE | 2023年 / 48卷 / 08期

基金：

中国国家自然科学基金;

关键词：

F-18-FDG; Ga-68-FAPI; Ga-68-PSMA; neuroendocrine adenocarcinoma; neuroendocrine prostate cancer; PET/CT;

D O I：

10.1097/RLU.0000000000004719

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Mixed neuroendocrine carcinoma-acinar carcinoma is an uncommon histological type of neuroendocrine prostate cancer. It has been rarely reported in de novo prostate malignancies. In this case, we present Ga-68-PSMA (prostate-specific membrane antigen), Ga-68-FAPI, and F-18-FDG PET/CT findings in the de novo form of mixed large-cell neuroendocrine carcinoma-acinar adenocarcinoma of the prostate. Different levels of radiotracer uptake were observed in different metastatic sites on Ga-68-PSMA, Ga-68-FAPI, and F-18-FDG PET/CT. This case demonstrates that the multitracer PET/CT strategy may be used for the noninvasive detection of the intermetastatic heterogeneity in metastatic neuroendocrine prostate cancer.

引用

页码：743 / 745

页数：3

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