Novel growth hormone receptor antagonist with discrete PEGylations markedly improve response to therapy in human pancreatic and bile duct cancers in mice

被引:1
|
作者
Basu, Reetobrata
Kopchick, John J.
机构
关键词
D O I
10.1158/1538-7445.AM2023-408
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
408
引用
收藏
页数:2
相关论文
共 39 条
  • [21] Gene expression profiling of breast cancers between high and low Ki-67 after short-term preoperative hormone therapy among hormone receptor-positive / human epidermal growth factor receptor 2-negative breast cancers with high Ki-67
    Kajiwara, Yukiko
    Iwamoto, Takayuki
    Otani, Yusuke
    Fujihara, Miwa
    Suzuki, Yoko
    Hatono, Minami
    Tsukioki, Takahiro
    Kawada, Kengo
    Kochi, Mariko
    Ikeda, Hirokuni
    Shien, Tadahiko
    Taira, Naruto
    Doihara, Hiroyoshi
    CANCER RESEARCH, 2020, 80 (04)
  • [22] APOBEC Mutational Signatures in Hormone Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative Breast Cancers Are Associated With Poor Outcomes on CDK4/6 Inhibitors and Endocrine Therapy
    Sammons, Sarah
    Raskina, Kira
    Danziger, Natalie
    Alder, Laura
    Schrock, Alexa B.
    Venstrom, Jeffrey M.
    Knutson, Keith L.
    Thompson, E. Aubrey
    McGregor, Kim
    Sokol, Ethan
    Chumsri, Saranya
    JCO PRECISION ONCOLOGY, 2022, 6
  • [23] A novel mutation affecting the interdomain link region of the growth hormone receptor in a Vietnamese girl, and response to long-term treatment with recombinant human insulin-like growth factor-I and luteinizing hormone-releasing hormone analogue
    Walker, JL
    Crock, PA
    Behncken, SN
    Rowlinson, SW
    Nicholson, LM
    Boulton, TJC
    Waters, MJ
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (07): : 2554 - 2561
  • [24] Z-360, a Novel Cholecystokinin-2/Gastrin Receptor Antagonist, Inhibits Gemcitabine-Induced Expression of the Vascular Endothelial Growth Factor Gene in Human Pancreatic Cancer Cells
    Kobayashi, Nobuyoshi
    Seto, Koichi
    Orikawa, Yuki
    Hamano, Hiroki
    Yoshinaga, Koji
    Takei, Mineo
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2010, 33 (02) : 216 - 222
  • [25] Targeted therapy of human pancreatic cancer with RPR127963E, a novel inhibitor of platelet-derived growth factor receptor, in an orthotopic nude mouse model
    Hwang, RF
    Bucana, C
    Killion, J
    Evans, DB
    Fidler, IJ
    ANNALS OF SURGICAL ONCOLOGY, 2003, 10 (01) : S23 - S23
  • [26] MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial
    Chien, A. Jo
    Tripathy, Debasish
    Albain, Kathy S.
    Symmans, W. Fraser
    Rugo, Hope S.
    Melisko, Michelle E.
    Wallace, Anne M.
    Schwab, Richard
    Helsten, Teresa
    Forero-Torres, Andres
    Stringer-Reasor, Erica
    Ellis, Erin D.
    Kaplan, Henry G.
    Nanda, Rita
    Jaskowiak, Nora
    Murthy, Rashmi
    Godellas, Constantine
    Boughey, Judy C.
    Elias, Anthony D.
    Haley, Barbara B.
    Kemmer, Kathleen
    Isaacs, Claudine
    Clark, Amy S.
    Lang, Julie E.
    Lu, Janice
    Korde, Larissa
    Edmiston, Kirsten K.
    Northfelt, Donald W.
    Viscusi, Rebecca K.
    Yee, Douglas
    Perlmutter, Jane
    Hylton, Nola M.
    van't Veer, Laura J.
    DeMichele, Angela
    Wilson, Amy
    Peterson, Garry
    Buxton, Meredith B.
    Paoloni, Melissa
    Clennell, Julia
    Berry, Scott
    Matthews, Jeffrey B.
    Steeg, Katherine
    Singhrao, Ruby
    Hirst, Gillian L.
    Sanil, Ashish
    Yau, Christina
    Asare, Smita M.
    Berry, Donald A.
    Esserman, Laura J.
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (10) : 1059 - +
  • [27] Effect of Z-360, a novel orally active CCK-2/gastrin receptor antagonist on tumor growth in human pancreatic adenocarcinoma cell lines in vivo and mode of action determinations in vitro
    Kawasaki, Daisuke
    Emori, Yutaka
    Eta, Runa
    Iino, Yuka
    Hamano, Hiroki
    Yoshinaga, Koji
    Tanaka, Takao
    Takei, Mineo
    Watson, Susan A.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2008, 61 (05) : 883 - 892
  • [28] Effect of Z-360, a novel orally active CCK-2/gastrin receptor antagonist on tumor growth in human pancreatic adenocarcinoma cell lines in vivo and mode of action determinations in vitro
    Daisuke Kawasaki
    Yutaka Emori
    Runa Eta
    Yuka Iino
    Hiroki Hamano
    Koji Yoshinaga
    Takao Tanaka
    Mineo Takei
    Susan A. Watson
    Cancer Chemotherapy and Pharmacology, 2008, 61 : 883 - 892
  • [29] In vivo imaging of therapy response to novel antibody mixtures targeted at the human epidermal growth factor receptor family using FDG and FLT positron emission tomography
    Nielsen, Carsten H.
    Jensen, Mette M.
    Jacobsen, Helle J.
    Poulsen, Thomas T.
    Horak, Ivan D.
    Lantto, Johan
    Kragh, Michael
    Kjaer, Andreas
    CANCER RESEARCH, 2014, 74 (19)
  • [30] Somatostatin receptor (SSTR) subtype-selective analogues differentially suppress in vitro growth hormone and prolactin in human pituitary adenomas - Novel potential therapy for functional pituitary tumors
    Shimon, I
    Yan, XM
    Taylor, JE
    Weiss, MH
    Culler, MD
    Melmed, S
    JOURNAL OF CLINICAL INVESTIGATION, 1997, 100 (09): : 2386 - 2392