Demethylzeylasteral targets lactate to suppress the tumorigenicity of liver cancer stem cells: It is attributed to histone lactylation?

被引：1
|
作者：
Gong, Hang [1 ]
Xu, Hui-Mei [1 ]
Ma, Yao-Hui [1 ]
Zhang, De-Kui [1 ]
机构：
[1] Lanzhou Univ, Dept Gastroenterol, Hosp 2, Lanzhou, Gansu, Peoples R China
来源：
PHARMACOLOGICAL RESEARCH | 2023年 / 194卷
关键词：
Histone lactylation; Lactate; Glycolysis; Liver cancer; Tumorigenicity;
D O I：
10.1016/j.phrs.2023.106869
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells
    Di Martile, Marta
    Desideri, Marianna
    De Luca, Teresa
    Gabellini, Chiara
    Buglioni, Simonetta
    Eramo, Adriana
    Sette, Giovanni
    Milella, Michele
    Rotili, Dante
    Mai, Antonello
    Carradori, Simone
    Secci, Daniela
    De Maria, Ruggero
    Del Bufalo, Donatella
    Trisciuoglio, Daniela
    ONCOTARGET, 2016, 7 (10) : 11332 - 11348
  • [42] The histone acetyltransferase inhibitor CPTH6 selectively targets lung cancer stem-like cells
    Di Martile, Marta
    Desideri, Mariannna
    De Luca, Teresa
    Gabellini, Chiara
    Eramo, Adriana
    Milella, Michele
    Secci, Daniela
    Carradori, Simone
    Buglioni, Simona
    Del Bufalo, Donatella
    Trisciuoglio, Daniela
    CANCER RESEARCH, 2015, 75
  • [43] Histone deacetylase inhibitors for the treatment of cancer stem cells
    Dvorakova, M.
    Vanek, T.
    MEDCHEMCOMM, 2016, 7 (12) : 2217 - 2231
  • [44] Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer
    Trisciuoglio, Daniela
    Di Martile, Marta
    Del Bufalo, Donatella
    STEM CELLS INTERNATIONAL, 2018, 2018
  • [45] Lactate Modulates Cellular Metabolism Through Histone Lactylation-Mediated Gene Expression in Non-Small Cell Lung Cancer
    Jiang, Jun
    Huang, DengLiang
    Jiang, Yuan
    Hou, Jing
    Tian, MeiYuan
    Li, JianHua
    Sun, Li
    Zhang, YaoGang
    Zhang, Tao
    Li, ZhiQin
    Li, ZhongCheng
    Tong, SiXian
    Ma, YanYan
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [46] Stem cells, cancer, liver, and liver cancer stem cells: Finding a way out of the labyrinth...
    Piscaglia, A. C.
    Shupe, T. D.
    Petersen, B. E.
    Gasbarrini, A.
    CURRENT CANCER DRUG TARGETS, 2007, 7 (06) : 582 - 590
  • [47] ADULT STEM CELLS FOUND TO SUPPRESS CANCER WHILE DORMANT
    不详
    STEM CELLS TRANSLATIONAL MEDICINE, 2014, 3 (02) : XIV - XIV
  • [48] Targeting cancer stem cells to suppress acquired chemotherapy resistance
    Vidal, S. J.
    Rodriguez-Bravo, V.
    Galsky, M.
    Cordon-Cardo, C.
    Domingo-Domenech, J.
    ONCOGENE, 2014, 33 (36) : 4451 - 4463
  • [49] Targeting cancer stem cells to suppress acquired chemotherapy resistance
    S J Vidal
    V Rodriguez-Bravo
    M Galsky
    C Cordon-Cardo
    J Domingo-Domenech
    Oncogene, 2014, 33 : 4451 - 4463
  • [50] Biomaterials to suppress cancer stem cells and disrupt their tumoral niche
    Garcia-Mazas, Carla
    Csaba, Noemi
    Garcia-Fuentes, Marcos
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017, 523 (02) : 490 - 505
12345