Ischemic stroke;
Carotid;
Stroke risk prediction;
Deep learning;
3D image segmentation;
ARTERY SEGMENTATION;
ANGIOGRAPHY;
NETWORK;
LUMEN;
NET;
D O I:
10.1007/s12539-023-00583-x
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Stroke is still the World's second major factor of death, as well as the third major factor of death and disability. Ischemic stroke is a type of stroke, in which early detection and treatment are the keys to preventing ischemic strokes. However, due to the limitation of privacy protection and labeling difficulties, there are only a few studies on the intelligent automatic diagnosis of stroke or ischemic stroke, and the results are unsatisfactory. Therefore, we collect some data and propose a 3D carotid Computed Tomography Angiography (CTA) image segmentation model called CA-UNet for fully automated extraction of carotid arteries. We explore the number of down-sampling times applicable to carotid segmentation and design a multi-scale loss function to resolve the loss of detailed features during the process of down-sampling. Moreover, based on CA-Unet, we propose an ischemic stroke risk prediction model to predict the risk in patients using their 3D CTA images, electronic medical records, and medical history. We have validated the efficacy of our segmentation model and prediction model through comparison tests. Our method can provide reliable diagnoses and results that benefit patients and medical professionals.
机构:
Univ Liverpool, Dept Math Sci, Liverpool, Merseyside, England
Natl Tsing Hua Univ, Ctr Cognit & Mind Sci, Hsinchu, Taiwan
Natl Tsing Hua Univ, Int Intercoll PhD Programme, Hsinchu, TaiwanUniv Liverpool, Dept Math Sci, Liverpool, Merseyside, England
Bal, Sukhdeep Singh
Chen, Ke
论文数: 0引用数: 0
h-index: 0
机构:
Univ Liverpool, Dept Math Sci, Liverpool, Merseyside, EnglandUniv Liverpool, Dept Math Sci, Liverpool, Merseyside, England
Chen, Ke
Yang, Fan-Pei Gloria
论文数: 0引用数: 0
h-index: 0
机构:
Natl Tsing Hua Univ, Ctr Cognit & Mind Sci, Hsinchu, Taiwan
Natl Tsing Hua Univ, Dept Foreign Languages & Literature, Hsinchu, Taiwan
Osaka Univ, Grad Sch Dent, Dept Radiol, Osaka, Japan
101,Sect 2,Guangfu Rd, Hsinchu, TaiwanUniv Liverpool, Dept Math Sci, Liverpool, Merseyside, England
Yang, Fan-Pei Gloria
Peng, Giia-Sheun
论文数: 0引用数: 0
h-index: 0
机构:
Natl Def Med Ctr, Triserv Gen Hosp, Dept Neurol, Taipei, Taiwan
Taipei Vet Gen Hosp, Dept Internal Med, Div Neurol, Hsinchu Branch, Hsinchu, TaiwanUniv Liverpool, Dept Math Sci, Liverpool, Merseyside, England
机构:
Tongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Fan, Jiahui
Li, Xiaoguang
论文数: 0引用数: 0
h-index: 0
机构:
Tongji Univ, Dept Thyroid Breast & Vasc Surg, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Li, Xiaoguang
Yu, Xueying
论文数: 0引用数: 0
h-index: 0
机构:
Tongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Yu, Xueying
Liu, Zhenqiu
论文数: 0引用数: 0
h-index: 0
机构:
Fudan Univ, State Key Lab Genet Engn, Shanghai, Peoples R China
Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Sch Life Sci, Shanghai, Peoples R China
Fudan Univ, Taizhou Inst Hlth Sci, Shanghai, Peoples R China
Fudan Univ, Human Phenome Inst, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Liu, Zhenqiu
Jiang, Yanfeng
论文数: 0引用数: 0
h-index: 0
机构:
Fudan Univ, State Key Lab Genet Engn, Shanghai, Peoples R China
Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Sch Life Sci, Shanghai, Peoples R China
Fudan Univ, Taizhou Inst Hlth Sci, Shanghai, Peoples R China
Fudan Univ, Human Phenome Inst, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Jiang, Yanfeng
Fang, Yibin
论文数: 0引用数: 0
h-index: 0
机构:
Tongji Univ, Shanghai Peoples Hosp 4, Sch Med, Dept Neurovasc Dis, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Fang, Yibin
Zong, Ming
论文数: 0引用数: 0
h-index: 0
机构:
Tongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Zong, Ming
Suo, Chen
论文数: 0引用数: 0
h-index: 0
机构:
Fudan Univ, Taizhou Inst Hlth Sci, Shanghai, Peoples R China
Fudan Univ, Sch Publ Hlth, Dept Epidemiol, Minist Educ, Shanghai, Peoples R China
Fudan Univ, Sch Publ Hlth, Key Lab Publ Hlth Safety, Minist Educ, Shanghai, Peoples R China
Fudan Univ, Shanghai Inst Infect Dis & Biosecur, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Suo, Chen
Man, Qiuhong
论文数: 0引用数: 0
h-index: 0
机构:
Tongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China
Man, Qiuhong
Xiong, Lize
论文数: 0引用数: 0
h-index: 0
机构:
Tongji Univ, Shanghai Peoples Hosp 4, Sch Med, Dept Anesthesiol & Perioperat Med, Shanghai, Peoples R China
Translat Res Inst Brain & Brain Like Intelligence, Shanghai, Peoples R China
Shanghai Key Lab Anesthesiol & Brain Funct Modulat, Shanghai, Peoples R ChinaTongji Univ, Dept Clin Lab, Shanghai Peoples Hosp 4, Sch Med, Shanghai, Peoples R China