COVID-19: Inhaled galectin-3 inhibitor safe and effective?

被引：0
|
作者：
Simon, Annika
机构：
来源：
PNEUMOLOGIE | 2023年 / 77卷 / 09期
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D O I：
10.1055/a-2038-6796
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Eine hohe Konzentration von zirkulierendem Galektin-3 wird mit schlechtem Outcome bei Betroffenen einer Coronavirus-Erkrankung (COVID-19) in Verbindung gebracht. In diesem Kontext wollten Gaughan et al. die Hypothese prufen, dass GB0139, ein potenter inhalativer Thiodigalactosid-Galektin-3-Inhibitor mit entzundungshemmender Wirkung, bei COVID-19-Pneumonitis sicher und wirksam ware, und stellen nun ihre Phase-Ib/IIa-Studie zum Thema vor.
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